BAF155 Background Information The SWI/SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF1 or SNF2å) and Brg-1 (also designated SNF2 or SNF2∫) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
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BAF155 (DXD7)
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BAF155 (DXD7): sc-32763. Western blot analysis of BAF155 expression in Jurkat (A) and HeLa (B) nuclear extracts.
BAF155 (DXD7): sc-32763. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing nuclear staining of lymphoid cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
BAF155 (DXD7): sc-32763. Western blot analysis of BAF155 expression in non-transfected 293T: sc-117752 (A), human BAF155 transfected 293T: sc-111379 (B) and K-562 (C) whole cell lysates.
BAF155 (DXD7): sc-32763. Western blot analysis of BAF155 expression in Jurkat whole cell lysate.
