BAF250a Background Information The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2å) and Brg-1 (also designated SNF2ß) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID 1A) and BAF250b(ARID1B), are thought to play regulatory roles.
BAF250a (PSG3) Product Citations
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BAF250a (PSG3): sc-32761. Immunoperoxidase staining of formalin fixed, paraffin-embedded human salivary gland tissue showing nuclear staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
BAF250a (PSG3): sc-32761. Western blot analysis of BAF250a expression in SH-SY5Y (A) and Y79 (B) whole cell lysates. Note presence of BAF250a degradation products.
BAF250a (PSG3): sc-32761. Western blot analysis of BAF250a expression in Y79 whole cell lysate.