KLRG1 Background Information Killer cell lectin-like receptor G1 (KLRG1) is expressed as a homodimer, composed of glycosylated 30-38 kDa subunits, on natural killer (NK) cells and activated CD8 T cells. KLRG1 expression is tightly regulated and is induced through different molecular mechanisms in varying subsets of immune-responsive cells. Induction of the receptor leads to inhibition of NK cell-mediated cytotoxicity and cytokine production, indicating a role for KLRG1 in the termination of NK cell activation. A rat homologue of KLRG1, designated mast cell function-associated antigen (MAFA), was originally islolated from the RBL-2H3 cell line. MAFA is expressed in rat mast cells and basophils.
KLRG1 (2F1)
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KLRG1 (2F1) PE: sc-32755 PE. FCM analysis of RBL-2H3 cells. Black line histogram represents the isotype control, normal Syrian hamster IgG.
