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p-NFATc4 (Ser 168/170) Antibody: sc-32630 |
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- rabbit polyclonal IgG, 200 µg/ml
- recommended for detection of Ser 168 and Ser 170 dually phosphorylated NFATc4 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
- blocking peptide, sc-32630 P
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NFATc4 Background Information
NFATc4 (nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4) is a member of the nuclear factors of activated T cells DNA-binding transcription complex that influences cytokine gene expression, cardiac hypertrophy, and adipocyte differentiation. This complex consists of at least two components: a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues, including Serine-168 and Serine-170, in the NFAT homology domain of NFATc4.
| p-NFATc4 (Ser 168/170) Product Citations |
See how others have used p-NFATc4 (Ser 168/170): sc-32630 antibody and or p-NFATc4 (Ser 168/170) antibody conjugates.
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p-NFATc4 (Ser 168/170)
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p-NFATc4 (Ser 168/170): sc-32630. Western blot analysis of NFATc4 phosphorylation in non-transfected: sc-117752 (A) and human NFATc4 transfected: sc-116481 (B) 293T whole cell lysates. p-NFATc4 (Ser 168/170): sc-32630. Western blot analysis of NFATc4 phosphorylation in non-transfected: sc-117752 (A) and mouse NFATc4 transfected: sc-122039 (B) 293T whole cell lysates. Western blot analysis of NFATc4 phosphorylation in untreated (A, C) and lambda protein phosphatase treated (B, D) Jurkat whole cell lysates. Antibodies tested include p-NFATc4 (Ser 168/170): sc-32630 (A, B) and NFATc4 (H-74): sc-13036 (C, D). p-NFATc4 (Ser 168/170): sc-32630. Western blot analysis of NFATc4 phosphorylation in untreated (A) and lambda protein phosphatase treated (B) Jurkat nuclear extracts.
p-NFATc4 (Ser 168/170): sc-32630.Western blot analysis of NFATc4 phosphorylation in untreated (A) and lambda protein phosphatase treated (B) Jurkat whole cell lysates.
Western blot analysis of NFATc4 phosphorylation in untreated (A,C), and lambda protein phosphatase treated (B,D) Jurkat whole cell lysates. Antibodies tested include p-NFATc4 (Ser 168/170): sc-32630 (A,B) and NFATc4 (C-20): sc-1153 (C,D). Western blot analysis of NFATc4 phosphorylation in untreated (A,C), and lambda protein phosphatase treated (B,D) Jurkat nuclear extract. Antibodies tested include p-NFATc4 (Ser 168/170): sc-32630 (A,B) and NFATc4 (C-20): sc-1153 (C,D). |
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