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p-Dab2 Antibody (Ser 24): sc-32573

 |  Datasheet

(Based on data analysis)

  • p-Dab2 Antibody (Ser 24) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to phosphorylated Ser 24 of Dab2 of human origin
  • recommended for detection of Ser 24 phosphorylated Dab2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
  • blocking peptide, sc-32573 P
  • See 1 citations for p-Dab2 Antibody (Ser 24)
 

See additional Dab Antibodies including Dab, Dab1 and Dab2.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-Dab2 Antibody (Ser 24) sc-32573 200 µg/ml $279
p-Dab2 (Ser 24) P sc-32573 P
(peptide)
 100 µg/0.5 ml $61
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Dab2 siRNA (h) sc-35167 10 µM $258
Dab2 siRNA (m) sc-35168 10 µM $258
Dab2 (h)-PR sc-35167-PR 10 µM, 20 µl $23
Dab2 (m)-PR sc-35168-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Dab2 shRNA Plasmid (h) sc-35167-SH 20 µg $520
Dab2 shRNA Plasmid (m) sc-35168-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Dab2 shRNA (h) Lentiviral Particles sc-35167-V 200 µl $625
Dab2 shRNA (m) Lentiviral Particles sc-35168-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Y79 Cell Lysate sc-2240 500 µg/200 µl $104
Dab2 (h2): 293T Lysate sc-172931 100 µg/200 µl $205
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human DAB2 1601 5p13.1 NM_001343 P98082
 n/a
Mouse Dab2 13132 15 A1 P98078
 N/A
 

Dab2 (also designated DOC-2) is a mitogen-responsive phosphoprotein that binds the SH3 domain of Grb2, and it is thought to be a negative regulator of growth. Dab2 Ser24 phosphorylation promotes membrane translocation of Dab2 and its subsequent interaction with integrin beta3, thereby defining a mechanism for Dab2 in regulating CD61 activation and inside-out signaling. Dab2 Ser24 phosphorylation is also involved in the negative regulation of CD61-induced T cell factor (TCF) transcriptional activity. Dab2 elicits distinct regulatory mechanisms in CD61 and -catenin/plakoglobin signaling in a Ser24 phosphorylation-dependent and -independent manner, respectively. Dab1, a homolog of the Drosophila Disabled protein, is an adaptor protein involved in neural development.

p-Dab2 Antibody (Ser 24) Product Citations
See how others have used p-Dab2 Antibody (Ser 24) and or p-Dab2 Antibody (Ser 24) conjugates.


1 total citations
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p-Dab2 Antibody (Ser 24) Data
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sc-32573
p-Dab2 (Ser 24): sc-32573. Western blot analysis of Dab2 phosphorylation in non-transfected 293T: sc-117752 (A), mouse Dab2 transfected 293T: sc-119652 (B) and Y79 (C) whole cell lysates.
sc-32573
p-Dab2 (Ser 24): sc-32573. Western blot analysis of Dab2 phosphorylation in non-transfected: sc-117752 (A) and human Dab2 transfected: sc-172931 (B) 293T whole cell lysates.
sc-32573
p-Dab2 (Ser 24): sc-32573. Western blot analysis of Dab2 phosphorylation in untreated (A) and lambda protein phosphatase treated HeLa whole cell lysates (B).
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