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home » Transcription Regulators » HIF Antibody / HIF Antibodies » HIF-3α (V-15): sc-32141

HIF-3α (V-15) Antibody: sc-32141

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the C-terminus of HIF-3α of mouse origin
  • recommended for detection of HIF-3α of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA
  • blocking peptide, sc-32141 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-32141 X, 200 µg/0.1 ml
 
Additional HIF Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human HIF3A 64344 19q13.32 NM_022462, NM_152794, NM_152795 Q9Y2N7
 609976
Mouse Hif3a 53417 7 A2 Q0VBL6
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
HIF-3α (V-15) sc-32141 200 µg/ml $279
HIF-3α (V-15) P sc-32141 P
(peptide)
 100 µg/0.5 ml $61
HIF-3α (V-15) X sc-32141 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HIF-3α siRNA (m) sc-38168 10 µM $258
HIF-3α (m)-PR sc-38168-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HIF-3α shRNA Plasmid (m) sc-38168-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HIF-3α shRNA (m) Lentiviral Particles sc-38168-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
mouse liver extract sc-2256 500 µg/200 µl $104
rat liver extract sc-2395 500 µg/200 µl $104

HIF-3α Background Information
Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1å, HIF-1∫ (also designated Arnt, EPAS-1 (also designated HIF-2å) and HIF-3å, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family . In response to hypoxia, HIF-1å is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription. Hypoxia-inducible expression of some genes such as Glut-1, p53, p21 or Bcl-2, is HIF-1å dependent, whereas expression of others, such as p27, GADD 153 or HO-1, is HIF-1å independent. EPAS-1 and HIF-3å have also been shown to form heterodimeric complexes with Arnt 1 in response to hypoxia.

HIF-3α (V-15) Product Citations
See how others have used HIF-3α (V-15): sc-32141 antibody and or HIF-3α (V-15) antibody conjugates.


1 total citations
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HIF-3α (V-15)
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sc-32141
HIF-3α (V-15): sc-32141. Western blot analysis of human recombinant HIF-3α fusion protein.
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