santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Transcription Regulators » XBP Antibody / XBP Antibodies » XBP-1 (R-14): sc-32136

XBP-1 (R-14) Antibody: sc-32136

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within an internal region of XBP-1 of human origin
  • recommended for detection of XBP-1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-32136 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-32136 X, 200 µg/0.1 ml
 
Additional XBP Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human XBP1 7494 22q12.1 NM_005080 P17861
 194355
Mouse Xbp1 22433 11 A1 O35426
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
XBP-1 (R-14) sc-32136 200 µg/ml $279
XBP-1 (R-14) P sc-32136 P
(peptide)
 100 µg/0.5 ml $61
XBP-1 (R-14) X sc-32136 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
XBP-1 siRNA (h) sc-38627 10 µM $258
XBP-1 siRNA (m) sc-38628 10 µM $258
XBP-1 (h)-PR sc-38627-PR 10 µM $23
XBP-1 (m)-PR sc-38628-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
XBP-1 shRNA Plasmid (h) sc-38627-SH 20 µg $520
XBP-1 shRNA Plasmid (m) sc-38628-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
XBP-1 shRNA (h) Lentiviral Particles sc-38627-V 200 µl $625
XBP-1 shRNA (m) Lentiviral Particles sc-38628-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
BJAB nuclear extract sc-2145 1000 µg $143
MDA-MB-231 Cell Lysate sc-2232 500 µg/200 µl $104
Ramos nuclear extract sc-2153 1000 µg $143
U-87 MG Cell Lysate sc-2411 500 µg/200 µl $104
MDA-MB-231 Cell Lysate sc-2232 500 µg/200 µl $104
SK-BR-3 Cell Lysate sc-2218 500 µg/200 µl $104

XBP-1 Background Information
The X-box binding protein-1 (XBP-1 or hXBP-1), also designated tax-responsive element-binding protein 5 (TREB5) in mouse and human, or hepatocarcinogenesis-related transcription factor (HTF) in rat, belongs to the basic region/leucine zipper (bZIP) family of transcription factors. XBP-1 was first characterized as a protein that binds to the HLA-DRå promoter in B cells. XBP-1 recognizes the cAMP responsive element (CRE) in enhancers of human T cell leukemia virus and major histocompatibility complex class II genes and activates transcription of these genes. It is expressed at high levels in developing bone and its levels are modulated during osteoblast development, suggesting a role in regulation of expression of osteoblast-specific genes. In addition to binding to CRE sequences, XBP-1 has been shown to bind to TPA response elements (TREs).

XBP-1 (R-14) Product Citations
See how others have used XBP-1 (R-14): sc-32136 antibody and or XBP-1 (R-14) antibody conjugates.


1 total citations
Loading citations.
 
XBP-1 (R-14)
Click on image to enlarge
sc-32136
XBP-1 (R-14): sc-32136. Western blot analysis of XBP-1 expression in U-87 MG (A) and MDA-MB-231 (B) whole cell lysates and SK-BR-3 nuclear extract (C).
sc-32136
XBP-1 (R-14): sc-32136. Western blot analysis of XBP-1 expression in BJAB nuclear extract.
sc-32136
XBP-1 (R-14): sc-32136. Western blot analysis of XBP-1 expression in Ramos whole cell lysate.
sc-32136
XBP-1 (R-14): sc-32136. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar, nuclear and cytoplasmic localization.
Download
Datasheets
Get Adobe Acrobat Reader