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- goat polyclonal IgG, 200 µg/ml
- epitope mapping within an internal region of VDAC2 of human origin
- recommended for detection of VDAC2 and, to a lesser extent, VDAC1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-32059 P
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
VDAC2 |
7417 |
10q22.2 |
NM_003375 |
P45880
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193245 |
| Mouse |
Vdac2 |
22334 |
14 A3 |
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Q60930
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N/A |
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VDAC2 Background Information
Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential.
| VDAC2 (K-16) Product Citations |
See how others have used VDAC2 (K-16): sc-32059 antibody and or VDAC2 (K-16) antibody conjugates.
2 total citations Loading citations.
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VDAC2 (K-16)
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VDAC2 (K-16): sc-32059. Western blot analysis of VDAC2 expression in Jurakt whole cell lysate.
VDAC2 (K-16): sc-32059. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
VDAC2 (K-16): sc-32059. Immunoperoxidase staining of formalin fixed, paraffin-embedded human urinary bladder tissue showing cytoplasmic staining of squamous epithelial cells.
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