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GABAA Rβ1 (R-20) Antibody: sc-31426

 |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within a C-terminal cytoplasmic domain of GABAA Rβ1 of human origin
  • recommended for detection of GABAA Rβ1 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine and porcine
  • blocking peptide, sc-31426 P
 
Additional GABA Receptor Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human GABRB1 2560 4p12 NM_000812 P18505
137190
Mouse Gabrb1 14400 5 C3.2 P50571
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
GABAA Rβ1 (R-20) sc-31426 200 µg/ml $279
GABAA Rβ1 (R-20) P sc-31426 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
GABAA Rβ1 siRNA (h) sc-42437 10 µM $258
GABAA Rβ1 siRNA (m) sc-42438 10 µM $258
GABAA Rβ1 (h)-PR sc-42437-PR 10 µM $23
GABAA Rβ1 (m)-PR sc-42438-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
GABAA Rβ1 shRNA Plasmid (h) sc-42437-SH 20 µg $520
GABAA Rβ1 shRNA Plasmid (m) sc-42438-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
GABAA Rβ1 shRNA (h) Lentiviral Particles sc-42437-V 200 µl $625
GABAA Rβ1 shRNA (m) Lentiviral Particles sc-42438-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
mouse testis extract sc-2405 500 µg/200 µl $104
mouse brain extract sc-2253 500 µg/200 µl $104
rat brain extract sc-2392 500 µg/200 µl $104
mouse cerebellum extract sc-2403 500 µg/200 µl $104
rat cerebellum extract sc-2398 500 µg/200 µl $104

GABAA Rβ1 Background Information
GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (g-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rå1-6, GABAA R ∫1-3, GABAA R©1-3, GABAA R∂, GABAA Ré, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1å and GABAB R1∫. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2 and -3). The GABA transporters function to terminate GABA action.

GABAA Rβ1 (R-20)
Click on image to enlarge
GABAA Rβ1 (R-20): sc-31426. Western blot analysis of GABAA Rβ1 expression in mouse brain tissue extract.
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