 |
GABAA Rβ1 (R-20) Antibody: sc-31426 |
| Datasheet |
|
- goat polyclonal IgG, 200 µg/ml
- epitope mapping within a C-terminal cytoplasmic domain of GABAA Rβ1 of human origin
- recommended for detection of GABAA Rβ1 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine and porcine
- blocking peptide, sc-31426 P
|
|
| |
Ordering Information
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
GABRB1 |
2560 |
4p12 |
NM_000812 |
P18505
|
137190 |
| Mouse |
Gabrb1 |
14400 |
5 C3.2 |
|
P50571
|
N/A |
| |
GABAA Rβ1 Background Information GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (g-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rå1-6, GABAA R ∫1-3, GABAA R©1-3, GABAA R∂, GABAA Ré, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1å and GABAB R1∫. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2 and -3). The GABA transporters function to terminate GABA action. |
 |
|
GABAA Rβ1 (R-20)
Click on image to enlarge
|
|
GABAA Rβ1 (R-20): sc-31426. Western blot analysis of GABAA Rβ1 expression in mouse brain tissue extract.
|
|
Download
|
|