Date published: 2026-7-8

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UCP Antibodies

Santa Cruz Biotechnology features a diverse variety of UCP Antibodies for studying uncoupling proteins, which play a crucial role in regulating energy metabolism and thermogenesis in cells. UCP Antibodies support various research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Uncoupling proteins are integral to mitochondrial function, facilitating the dissipation of the proton gradient and thereby influencing ATP production and heat generation. Their regulation is vital for maintaining metabolic homeostasis and has implications in obesity, diabetes, and other metabolic disorders. Understanding uncoupling proteins can provide insights into essential physiological processes. Research applications include investigating mitochondrial energy transfer, cellular stress responses, and metabolic pathway regulation. Exploring uncoupling protein expression patterns helps reveal their role in different tissue types and physiological conditions. UCP research continues to uncover new connections between energy metabolism and various health conditions. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of energy metabolism and its impact on human health.

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UCP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

UCP1 Antibody (E-6)

sc-518171mouse IgG1 κ195-214 (h)WB, IP, IF, ELISAm, r, h
1
(1)

UCP1 Antibody (4E5)

sc-293418mouse IgG2a κ232-267 (h)WB, IP, ELISAm, r, h
24
(17)

UCP1 Antibody (A-6)

sc-518024mouse IgG2a κ284-307 (m)WB, IP, IF, IHC(P), ELISAm, r
7
(1)

UCP2 Antibody (G-6)

sc-390189mouse IgM κN-terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h
32
(27)

UCP4 Antibody (A-5)

sc-365295mouse IgM κ17-37 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(9)

UCP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

UCP1 siRNA (h)

sc-42680hGene SilencingN/A0
(0)

UCP1 shRNA Plasmid (h)

sc-42680-SHhGene SilencingPuromycin0
(0)

UCP1 shRNA (h) Lentiviral Particles

sc-42680-VhGene SilencingPuromycin0
(0)

UCP1 siRNA (m)

sc-42681mGene SilencingN/A
1
(0)

UCP1 shRNA Plasmid (m)

sc-42681-SHmGene SilencingPuromycin
1
(0)

UCP1 shRNA (m) Lentiviral Particles

sc-42681-VmGene SilencingPuromycin
1
(0)

UCP2 siRNA (h)

sc-42682hGene SilencingN/A
10
(0)

UCP2 shRNA Plasmid (h)

sc-42682-SHhGene SilencingPuromycin
10
(0)

UCP2 shRNA (h) Lentiviral Particles

sc-42682-VhGene SilencingPuromycin
10
(0)

UCP2 siRNA (m)

sc-42683mGene SilencingN/A
2
(0)

UCP2 shRNA Plasmid (m)

sc-42683-SHmGene SilencingPuromycin
2
(0)

UCP2 shRNA (m) Lentiviral Particles

sc-42683-VmGene SilencingPuromycin
2
(0)

UCP2 siRNA (I. tridecemlineatus)

sc-270660I. tridecemlineatusGene SilencingN/A0
(0)

UCP2 shRNA Plasmid (I. tridecemlineatus)

sc-270660-SHI. tridecemlineatusGene SilencingPuromycin0
(0)

UCP2 shRNA (I. tridecemlineatus) Lentiviral Particles

sc-270660-VI. tridecemlineatusGene SilencingPuromycin0
(0)

UCP2 (I. tridecemlineatus)-PR

sc-270660-PRI. tridecemlineatusPrimerN/A0
(0)

UCP3 siRNA (h)

sc-42684hGene SilencingN/A0
(0)

UCP3 shRNA Plasmid (h)

sc-42684-SHhGene SilencingPuromycin0
(0)

UCP3 shRNA (h) Lentiviral Particles

sc-42684-VhGene SilencingPuromycin0
(0)

UCP3 siRNA (m)

sc-42685mGene SilencingN/A
1
(0)

UCP3 shRNA Plasmid (m)

sc-42685-SHmGene SilencingPuromycin
1
(0)

UCP3 shRNA (m) Lentiviral Particles

sc-42685-VmGene SilencingPuromycin
1
(0)

UCP4 siRNA (h)

sc-36775hGene SilencingN/A0
(0)

UCP4 shRNA Plasmid (h)

sc-36775-SHhGene SilencingPuromycin0
(0)

UCP4 shRNA (h) Lentiviral Particles

sc-36775-VhGene SilencingPuromycin0
(0)

UCP4 siRNA (m)

sc-36776mGene SilencingN/A0
(0)

UCP4 shRNA Plasmid (m)

sc-36776-SHmGene SilencingPuromycin0
(0)

UCP4 shRNA (m) Lentiviral Particles

sc-36776-VmGene SilencingPuromycin0
(0)

UCP4 siRNA (I. tridecemlineatus)

sc-270662I. tridecemlineatusGene SilencingN/A0
(0)

UCP4 shRNA Plasmid (I. tridecemlineatus)

sc-270662-SHI. tridecemlineatusGene SilencingPuromycin0
(0)

UCP4 shRNA (I. tridecemlineatus) Lentiviral Particles

sc-270662-VI. tridecemlineatusGene SilencingPuromycin0
(0)

UCP4 (I. tridecemlineatus)-PR

sc-270662-PRI. tridecemlineatusPrimerN/A0
(0)

UCP CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

UCP1 CRISPR/Cas9 KO Plasmid (h)

sc-400410Gene Knockouth0
(0)

UCP1 HDR Plasmid (h)

sc-400410-HDRHomology Directed Repairh0
(0)

UCP1 CRISPR/Cas9 KO Plasmid (m)

sc-423595-KO-2Gene Knockoutm0
(0)

UCP1 HDR Plasmid (m2)

sc-423595-HDR-2Homology Directed Repairm0
(0)

UCP2 CRISPR/Cas9 KO Plasmid (h)

sc-400319Gene Knockouth0
(0)

UCP2 HDR Plasmid (h)

sc-400319-HDRHomology Directed Repairh0
(0)

UCP2 CRISPR/Cas9 KO Plasmid (m)

sc-423596Gene Knockoutm0
(0)

UCP2 HDR Plasmid (m)

sc-423596-HDRHomology Directed Repairm0
(0)

UCP3 CRISPR/Cas9 KO Plasmid (h)

sc-400866Gene Knockouth0
(0)

UCP3 CRISPR/Cas9 KO Plasmid (m)

sc-423597Gene Knockoutm0
(0)

UCP CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

UCP2 Double Nickase Plasmid (h)

sc-400319-NICGene Knockouth0
(0)

UCP2 Double Nickase Plasmid (h2)

sc-400319-NIC-2Gene Knockouth0
(0)

UCP4 Double Nickase Plasmid (h)

sc-417530-NICGene Knockouth0
(0)

UCP4 Double Nickase Plasmid (h2)

sc-417530-NIC-2Gene Knockouth0
(0)

UCP CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

UCP1 CRISPR Activation Plasmid (h)

sc-400410-ACTGene Activationh0
(0)

UCP1 CRISPR Activation Plasmid (h2)

sc-400410-ACT-2Gene Activationh0
(0)

UCP2 CRISPR Activation Plasmid (h)

sc-400319-ACTGene Activationh0
(0)

UCP3 CRISPR Activation Plasmid (h)

sc-400866-ACTGene Activationh0
(0)

UCP3 CRISPR Activation Plasmid (h2)

sc-400866-ACT-2Gene Activationh0
(0)

UCP4 CRISPR Activation Plasmid (h)

sc-417530-ACTGene Activationh0
(0)