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home » Membrane Receptors » ACTR Antibody / ACTR Antibodies » ACTR-IB (I-15): sc-31297

ACTR-IB (I-15) Antibody: sc-31297

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within an extracellular domain of ACTR-IB of human origin
  • recommended for detection of ACTR-IB of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-31297 P
 
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Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ACVR1B 91 12q13.13 NM_004302, NM_020327, NM_020328 P36896
 601300
Mouse Acvr1b 11479 15 F2 Q61271
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
ACTR-IB (I-15) sc-31297 200 µg/ml $279
ACTR-IB (I-15) P sc-31297 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ACTR-IB siRNA (h) sc-40208 10 µM $258
ACTR-IB siRNA (m) sc-40209 10 µM $258
ACTR-IB (h)-PR sc-40208-PR 10 µM $23
ACTR-IB (m)-PR sc-40209-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ACTR-IB shRNA Plasmid (h) sc-40208-SH 20 µg $520
ACTR-IB shRNA Plasmid (m) sc-40209-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ACTR-IB shRNA (h) Lentiviral Particles sc-40208-V 200 µl $625
ACTR-IB shRNA (m) Lentiviral Particles sc-40209-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
mouse brain extract sc-2253 500 µg/200 µl $104

ACTR-IB Background Information
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1–6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

ACTR-IB (I-15) Product Citations
See how others have used ACTR-IB (I-15): sc-31297 antibody and or ACTR-IB (I-15) antibody conjugates.


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ACTR-IB (I-15)
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sc-31297
ACTR-IB (I-15): sc-31297. Western blot analysis of ACTR-IB expression in mouse brain tissue extract.
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