epitope mapping near the N-terminus of TRAP of human origin
recommended for detection of TRAP of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
TRAP Background Information Tartrate-resistant acid phosphatase (TRAP, ACP5) is an iron containing glycoprotein that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. TRAP is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAP is a relatively minor lysosomal enzyme which may be activated in certain pathologies such as Hodgkin’s disease and B- and T-cell leukemias. Receptor activator of NFkB ligand (RANKL) plays an essential role in osteoclast differentiation and activation by increasing the expression of protease osteoclast markers such as TRAP. TRAP has collagenolytic activity and plays a major role in ligament degradation.
TRAP (N-17) Product Citations
See how others have used TRAP (N-17): sc-30832 antibody and or TRAP (N-17) antibody conjugates.
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TRAP (N-17)
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TRAP (N-17): sc-30832. Western blot analysis of TRAP expression in non-transfected: sc-117752 (A) and human TRAP transfected: sc-178082 (B) 293T whole cell lysates.
