 |
- rabbit polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of MyoD of mouse origin
- recommended for detection of MyoD of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine and porcine
- blocking peptide, sc-304 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-304 X, 200 µg/0.1 ml
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
MYOD1 |
4654 |
11p15.1 |
NM_002478 |
P15172
|
159970 |
| Mouse |
Myod1 |
17927 |
7 B4 |
|
P10085
|
N/A |
| |
MyoD Background Information
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes MyoD, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either MyoD or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. MyoD transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. MyoD-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes.
| MyoD (C-20) Product Citations |
See how others have used MyoD (C-20): sc-304 antibody and or MyoD (C-20) antibody conjugates.
54 total citations Loading citations.
|
| |
|
|
|
MyoD (C-20)
Click on image to enlarge
|
|
MyoD (C-20): sc-304. Western blot analysis of MyoD expression in A-673 (A) and Sol8 (B) nuclear extracts and C2C12 (C) and Sol8 (D) whole cell lysates.
|
|
Download
|
|
