epitope mapping near the N-terminus of ACAT-2 of human origin
recommended for detection of ACAT-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine and bovine
ACAT-2 Background Information ACAT-1 (acetyl-coenzyme A acetyltransferase 1) is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. Rare defects in the gene encoding ACAT-1 lead to ∫-ketothiolase deficiency, which is characterized by ketoacidotic attacks. ACAT-2 (acetyl-coenzyme A acetyltransferase 2) is considered a cytosolic protein and is crucial for cholesterol synthesis. Specifically, both acetoacetyl-CoA specific thiolases, ACAT-1 and ACAT-2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction, the cleavage of acetoacetyl-CoA into two acetyl-CoA molecules.
ACAT-2 (N-15)
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ACAT-2 (N-15): sc-30279. Western blot analysis of ACAT-2 expression in Hep G2 whole cell lysate (A) and mouse liver tissue extract (B).
ACAT-2 (N-15): sc-30279. Western blot analysis of ACAT-2 expression in non-transfected: sc-117752 (A) and mouse ACAT-2 transfected: sc-118189 (B) 293T whole cell lysates.
ACAT-2 (N-15): sc-30279. Western blot analysis of ACAT-3 expression in non-transfected: sc-117752 (A) and mouse ACAT-3 transfected: sc-118191 (B) 293T whole cell lysates and mouse liver tissue extract (C).
ACAT-2 (N-15): sc-30279. Western blot analysis of ACAT-2 expression in non-transfected: sc-117752 (A) and mouse ACAT-2 transfected: sc-118190 (B) 293T whole cell lysates and mouse liver tissue extract (C).
