 |
- rabbit polyclonal IgG, 200µg/ml
- epitope corresponding to amino acids 76-225 mapping within an internal region of DEK of human origin
- recommended for detection of DEK of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
DEK |
7913 |
6p22.3 |
NM_003472 |
P35659
|
125264 |
| Mouse |
Dek |
110052 |
13 A5 |
|
Q7TNV0
|
N/A |
| |
DEK Background Information
The mammalian nuclear phosphoprotein DEK is implicated in multiple cellular processes, including transcriptional regulation, mRNA processing, and chromatin remodeling, and is associated with a number of clinical autoimmune and neoplastic conditions (1). DEK, an abundant chromatin-associated protein, changes the topology of DNA in chromatin in vitro (2,3). Although first identified in a fusion with the CAN/Nup214 nucleoporin protein in a specific subtype of acute myelogenous leukemia, DEK is also an autoantigen in patients with pauciarticular onset juvenile rheumatoid arthritis (4-6). Furthermore, the last 65 amino acids of DEK can partially reverse the mutation-prone phenotype of cells from patients with ataxia-telangiectasia (4). The human DEK gene maps to chromosome 6p23(1).
| DEK (H-300) Product Citations |
See how others have used DEK (H-300): sc-30213 antibody and or DEK (H-300) antibody conjugates.
1 total citations Loading citations.
|
| |
|
|
|
DEK (H-300)
Click on image to enlarge
|
|
DEK (H-300): sc-30213. Western blot analysis of DEK expression in 293T (A) and HeLa (B) whole cell lysates.
DEK (H-300): sc-30213. Western blot analysis of DEK expression in K-562 nuclear extract.
|
|
Download
|
|
