Date published: 2025-9-10

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CoREST Antibodies

Santa Cruz Biotechnology features a diverse variety of CoREST monoclonal antibodies for advanced research in epigenetics and gene regulation. CoREST monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CoREST, or Co-repressor of Repressor Element-1 Silencing Transcription, plays a central role in regulating gene expression by modulating chromatin structure and recruiting histone deacetylases. Research has shown significant involvement of CoREST in neural development, with important implications in cancer and neurodegenerative diseases. Understanding CoREST function provides valuable insights into transcriptional repression mechanisms and cellular epigenetic landscapes. Investigating CoREST activity helps reveal fundamental aspects of gene regulation and cellular development. Recent studies have highlighted CoREST's role in maintaining cellular homeostasis and tissue-specific gene expression patterns. Exploring CoREST mechanisms contributes to our understanding of disease progression and potential therapeutic approaches. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific knowledge in gene regulation and epigenetic research.

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CoREST Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CoREST Antibody (H-8)

sc-376567mouse IgG1 κ431-469 (h)WB, IP, IF, ELISAm, r, h
5
(4)

CoREST Antibody (26)

sc-135873mouse IgG178-192 (h)WB, IP, IFm, r, h

new

(2)

CoREST CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CoREST CRISPR/Cas9 KO Plasmid (h)

sc-402066hGene KnockoutGFP0
(0)

CoREST HDR Plasmid (h)

sc-402066-HDRhHomology Directed RepairPuromycin0
(0)

CoREST Double Nickase Plasmid (h)

sc-402066-NIChGene KnockoutPuromycin0
(0)

CoREST Double Nickase Plasmid (h2)

sc-402066-NIC-2hGene KnockoutPuromycin0
(0)

CoREST CRISPR/Cas9 KO Plasmid (m)

sc-432260mGene KnockoutGFP0
(0)

CoREST HDR Plasmid (m)

sc-432260-HDRmHomology Directed RepairPuromycin0
(0)

CoREST Double Nickase Plasmid (m)

sc-432260-NICmGene KnockoutPuromycin0
(0)

CoREST Double Nickase Plasmid (m2)

sc-432260-NIC-2mGene KnockoutPuromycin0
(0)

CoREST CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CoREST CRISPR Activation Plasmid (h)

sc-402066-ACThGene ActivationPuro, Blast, Hygro0
(0)

CoREST CRISPR Activation Plasmid (h2)

sc-402066-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CoREST Lentiviral Activation Particles (h)

sc-402066-LAChGene ActivationPuro, Blast, Hygro0
(0)

CoREST Lentiviral Activation Particles (h2)

sc-402066-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CoREST CRISPR Activation Plasmid (m)

sc-432260-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CoREST CRISPR Activation Plasmid (m2)

sc-432260-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CoREST Lentiviral Activation Particles (m)

sc-432260-LACmGene ActivationPuro, Blast, Hygro0
(0)

CoREST Lentiviral Activation Particles (m2)

sc-432260-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CoREST siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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CoREST siRNA (h)

sc-38131hGene SilencingN/A0
(0)

CoREST shRNA Plasmid (h)

sc-38131-SHhGene SilencingPuromycin0
(0)

CoREST shRNA (h) Lentiviral Particles

sc-38131-VhGene SilencingPuromycin0
(0)

CoREST siRNA (m)

sc-142516mGene SilencingN/A0
(0)

CoREST shRNA Plasmid (m)

sc-142516-SHmGene SilencingPuromycin0
(0)

CoREST shRNA (m) Lentiviral Particles

sc-142516-VmGene SilencingPuromycin0
(0)