Phalloidin-Tetramethylrhodamine B isothiocyanate

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Synonym:	Phalloidin-TRITC
Application:	A fluorescent phallotoxin that can be used to identify filamentous actin
Molecular Weight:	1305.57
Molecular Formula:	C₆₂H₇₂N₁₂O₁₂S₄

This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.

Description

Phalloidin-Tetramethylrhodamine B isothiocyanate is a fluorescent phalloidin (sc-202763) derivative that can be used to identify filamentous actin. It binds polymeric F actin, stabilizing it and interfering with the function of actin-rich structures, and lowers the critical concentration of actin polymerization. The rhodamine moiety then allows for visualization of F-actin through fluorescence, with an excitation max of about 545 nm and an emission max of about 573 nm.

Technical Information

Appearance:	Solid
Physical State:	Solid
Solubility:	Soluble in water (0.5%), methanol, ethanol, butanol, and pyridine.
Storage:	Store at -20° C
Fluoresence:	λex 540-545 nm, λem 570-573 nm

Safety and Reference Information

Transport:	UN 2811, Class 6.1, Packing group II
WGK Germany:	3
MDL Number:	MFCD00278840

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Faulstich, H., et al. 1983. Exp. Cell Res. 144: 73-82. PMID: 6840214
2. Waggoner, A., et al. 1989. Methods Cell Biol. 30: 449-478. PMID: 2648118

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SDS

Datasheet/SDS