epitope corresponding to amino acids 301-346 mapping within an internal region of PACSIN1 of mouse origin
recommended for detection of PACSIN1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine and bovine
PACSIN1 Background Information PACSINs are members of a family of cytoplasmic adapter proteins, which share a conserved C-terminal protein binding SH3 domain and a CDC15-NT domain (1,2). PACSIN 1-related proteins include syndapin 1 (the rat homolog of PACSIN 1), FAP52, EM13, and PSTPIP, all of which seem to be involved in signaling pathways associated with cytoskeletal organization (3-6). PACSIN 1 expression is restricted to terminally differentiated neural tissue, whereas PACSIN 2 is widely expressed (1). PACSIN 2 shows vesicle-like distribution and may be involved in regulating endocytotic processes (2).
PACSIN1 (M-46) Product Citations
See how others have used PACSIN1 (M-46): sc-30127 antibody and or PACSIN1 (M-46) antibody conjugates.
1 total citations
Loading citations.
PACSIN1 (M-46)
Click on image to enlarge
PACSIN1 (M-46): sc-30127. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing cytoplasmic staining of cells in molecular and granular layers and Purkinje cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
PACSIN1 (M-46): sc-30127. Western blot analysis of PACSIN1 expression in non-transfected: sc-117752 (A) and mouse PACSIN1 transfected: sc-122348 (B) 293T whole cell lysates.
