Glutaraldehyde solution (CAS 111-30-8)

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Synonym:	Pentane-1,5-dial
Application:	A protein cross-linking agent
CAS Number:	111-30-8
Molecular Weight:	100.12
Molecular Formula:	OHC(CH₂)₃CHO

This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.

Description

Glutaraldehyde solution, 25% in water is primarily for use as a protein cross-linking agent. This grade is not recommended for use as an electron microscopy fixative. In the laboratory, glutaraldehyde solution is commonly used as an amine-reactive homobifunctional crosslinker and as a disinfectant for medical equipment. Glutaraldehyde may effectively crosslink amine and hydrazine derivatives to proteins and other amine-containing polymers; biotin hydrazides have been directly coupled to nucleic acids with glutaraldehyde in a reaction that is potentially useful for conjugating fluorescent hydrazides and hydroxylamines to DNA.

Technical Information

Formulation:	25% in water
Appearance:	Colorless
Physical State:	Liquid
Solubility:	Soluble in water, ethanol, benzene, and ether.
Storage:	Store at 4° C
Boiling Point:	100-102 °C
Density:	1.06 g/mL at 20 °C
Refractive Index:	n²⁰_D 1.37

Safety and Reference Information

Transport:	UN 2922, Class 8, 6.1, Packing group III
WGK Germany:	3
RTECS:	MA2450000
PubChem CID:	3485
Merck Index:	14: 4472
MDL Number:	MFCD00007025
EC Number:	203-856-5
Beilstein Registry:	605390
SMILES:	C(CC=O)CC=O

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Delcros, J.G., et al. 1995. J. Immunol. Methods. 185: 191-198. PMID: 7561129
2. Vuolanto, A., et al. 2004. Biotechnol. Prog. 20: 771-776. PMID: 15176881
3. Guo, J.B., et al. 2010. Anal. Chim. Acta. 658: 197-203. PMID: 20103095
4. Sai, N., et al. 2010. Talanta. 82: 1113-1121. PMID: 20801306

SDS

Datasheet/SDS