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CREB3L3 Antibody (H-148): sc-292135

 |  Datasheet

(Based on data analysis)

  • CREB3L3 Antibody (H-148) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 90-237 mapping within an internal region of CREB3L3 of human origin
  • recommended for detection of CREB3L3 of mouse and human origin by WB, IP, IF and ELISA
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-292135 X, 200 µg/0.1 ml
 
Full-length CREB3L3 protein sequence with immunogen highlighted:
MNTDLAAGKMASAACSMDPIDSFELLDLLFDRQDGILRHVELGEGWGHVKDQQVLPNPDSDDFLSSILGSGDSLPSSPLWSPEGSDSGISEDLPSDPQDTPPRSGPATSPAGCHPAQPGKGPCLSYHPGNSCSTTTPGPVIQVPEASVTIDLEMWSPGGRICAEKPADPVDLSPRCNLTVKDLLLSGSSGDLQQHHLGASYLLRPGAGHCQELVLTEDEKKLLAKEGITLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNLSLLEQLKKLQAIVVQSTSKSAQTGTCVAVLLLSFALIILPSISPFGPNKTESPGDFAPVRVFSRTLHNDAASRVAADAVPGSEAPGPRPEADTTREESPGSPGADWGFQDTANLTNSTEELDNATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGLEAAGDEL

See additional CREB3L Antibodies including CREB3L, CREB3L1, CREB3L2, CREB3L3 and CREB3L4.

Ordering InformationGene Info
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WB   IP   IF  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
CREB3L3 Antibody (H-148) sc-292135 200 µg/ml $279
CREB3L3 Antibody (H-148) X sc-292135 X 200 µg/0.1 ml $279
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CREB3L3 84699 19p13.3 NM_032607 Q68CJ9
 n/a
Mouse Creb3l3 208677 10 C1 NM_145365 Q91XE9
 N/A
 

CREB3L3 (cAMP-responsive element-binding protein 3-like protein 3), also known as CREBH or HYST1481, is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.
CREB3L3 Antibody (H-148) Data
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sc-292135
CREB3L3 (H-148): sc-292135. Western blot analysis of CREB3L3 expression in non-transfected: sc-117752 (A) and human CREB3L3 transfected: sc-370151 (B) 293T whole cell lysates and mouse liver tissue extract (C).
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