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Orai3 Antibody (H-51): sc-292104

 |  Datasheet

(Based on data analysis)

  • Orai3 Antibody (H-51) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1-51 mapping at the N-terminus of Orai3 of human origin
  • recommended for detection of Orai3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
 
Full-length Orai3 protein sequence with immunogen highlighted:
MKGGEGDAGEQAPLNPEGESPAGSATYREFVHRGYLDLMGASQHSLRALSRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESDHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPLDTPTPMVPTSRVPGTLAPVATSLSPASNLPRSSASAAPSQAEPACPPRQACGGGGAHGPGWQAAMASTAIMVPVGLVFVAFALHFYRSLVAHKTDRYKQELEELNRLQGELQAV

See additional Orai Antibodies including Orai, Orai1, Orai2 and Orai3.

Ordering InformationGene Info
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Orai3 Antibody (H-51) sc-292104 200 µg/ml $279
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ORAI3 93129 16p11.2 NM_152288 Q9BRQ5
 610930
 

Orai3 (ORAI calcium release-activated calcium modulator 3), also known as TMEM142C (transmembrane protein 142C), is a 295 amino acid multi-pass membrane protein that belongs to the Orai family of proteins. Localizing to the plasma membrane, Orai3 plays an important role in store-operated calcium (SOC) entry, a process involving Ca(2+) influx and replenishment of Ca(2+) stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca(2+) mobilizing agents. CRAC channels are responsible for mediating calcium influx in T cells and play an important role in the immune response. Orai3, specifically, also acts as a regulator or component of the nuclear import of transcription factor NFAT.
Orai3 Antibody (H-51) Data
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sc-292104
Orai3 (H-51): sc-292104. Western blot analysis of Orai3 expression in AML-193 (A) and A549 (B) whole cell lysates and human recombinant Orai3 fusion protein (C).
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