5′-O-(4,4′-dimethoxytrityl)-thymidine-3′-O-succinic acid (CAS 74405-40-6)
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5′-O-(4,4′-dimethoxytrityl)-thymidine-3′-O-succinic acid is a modified thymidine. This compound is used in the stepwise synthesis of oligonucleotides, particularly in solid-phase synthesis where the protection of hydroxyl groups is crucial. The protecting groups can be selectively removed to allow for the addition of the next nucleotide in the sequence. The protected nucleoside can be used to create custom DNA or RNA sequences with specific sequences for research, diagnostic, or therapeutic applications. This includes the synthesis of probes, primers, siRNA, and other oligonucleotides. The carboxylic acid functionality introduced by the succinic acid group allows for conjugation to various molecules, including fluorescent dyes, biotin, or peptides, enabling the creation of labeled probes or functionalized nucleic acids for molecular biology applications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5′-O-(4,4′-dimethoxytrityl)-thymidine-3′-O-succinic acid, 1 g | sc-291078 | 1 g | $43.00 | |||
5′-O-(4,4′-dimethoxytrityl)-thymidine-3′-O-succinic acid, 5 g | sc-291078A | 5 g | $129.00 |