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Glycine (CAS 56-40-6)

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Application:A compound used for polyacrylamide gel electrophoresis and Western blots
CAS Number:56-40-6
Purity:≥98%
Molecular Weight:75.07
Molecular Formula:C2H5NO2
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Glycine sc-29096 1 kg $53
Glycine sc-29096A 500 g $35
Glycine sc-29096B 3 kg $175
Glycine sc-29096C 10 kg $249
Description
Glycine is widely used as a buffer for a variety of immunological applications. It is frequently used in the preparation of TG Buffers (Tris-Glycine; sc-296648) where the buffer is used as a running and/or transfer buffer for polyacrylamide gel electrophoresis and western blotting. Glycine (100 mM, pH 2.0-2.5; sc-295018) is also used as an eluent in column chromatography. Glycine has been reported for use in the enzymatic determination of lactate using lactic dehydrogenase.
Technical Information
Appearance:White crystalline
Physical State:Solid
Solubility:Soluble in water (100 mg/ml), and acetone (slightly soluble). Insoluble in alcohol, and ether.
Storage:Store at room temperature
Melting Point:240 °C (lit.)(dec.)
Boiling Point:233 °C
Density:1.60 g/cm3 at 20 °C
Refractive Index:n20D 1.46 (Predicted)
IC50:Glycine receptor alpha-4 chain: IC50 = 6 µM (mouse); Glutamate NMDA receptor: IC50 = 0.2 µM (rat)
Ki Data:Glutamate NMDA receptor: Ki= 170 nM (rat)
Safety and Reference Information
WGK Germany:1
RTECS:MB7600000
PubChem CID:750
Merck Index:14: 4491
MDL Number:MFCD00008131
EC Number:200-272-2
Beilstein Registry:635782
SMILES:C(C(=O)O)N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Laemmli, U.K. 1970. Nature. 227: 680-685. PMID: 5432063
2. Towbin, H., et al. 1979. Proc. Natl. Acad. Sci. U.S.A. 76: 4350-4354. PMID: 388439
3. Shapiro, S., 1997. Neurosurgery. 40: 168-76; discussion 177. PMID: 8971839
4. Dubos, C., et al. 2003. Plant J. 35: 800-810. PMID: 12969432
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