Molecular structure of Ciprofloxacin HCl, CAS Number: 93107-08-5
Ciprofloxacin HCl (CAS 93107-08-5)
See product citations (21)
Alternate Names:
Ciprofloxacin HCl is also known as 3-Quiolinecarboxylic acid.
Application:
Ciprofloxacin HCl is a fluoroquinolone DNA gyrase/topoisomerase-targeting antibiotic often used in cell culture.
CAS Number:
93107-08-5
Purity:
≥98%
Molecular Weight:
367.80
Molecular Formula:
C17H18FN3O3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ciprofloxacin HCl is a highly active fluoroquinoline antibiotic effective against a broad spectrum of bacteria and mycoplasma with few known resistant strains. Ciprofloxacin HCl targets gyrases and topoisomerases inhibiting DNA unwinding. Ciprofloxacin HCl is effective at low concentrations (10 µg/ml) and can effectively eradicate mycoplasma in as little as 12 days. Ciprofloxacin HCl has been used as a plant fungicide and is an analog of Nalidixic Acid. Ciprofloxacin HCl shows a broad spectrum of antibacterial activity against gram positive and gram negative bacteria.
Ciprofloxacin HCl (CAS 93107-08-5) References
- Emerging mechanisms of fluoroquinolone resistance. | Hooper, DC. 2001. Emerg Infect Dis. 7: 337-41. PMID: 11294736
- Sensitive LC determination of ciprofloxacin in pharmaceutical preparations and biological fluids with fluorescence detection. | Zotou, A. and Miltiadou, N. 2002. J Pharm Biomed Anal. 28: 559-68. PMID: 12008135
- In vivo evaluation of interaction between aqueous seed extract of Garcinia kola Heckel and ciprofloxacin hydrochloride. | Esimone, CO., et al. 2002. Am J Ther. 9: 275-80. PMID: 12115015
- Uptake and release of ciprofloxacin-HCl from conventional and silicone hydrogel contact lens materials. | Hui, A., et al. 2008. Eye Contact Lens. 34: 266-71. PMID: 18779666
- Zero-order controlled release of ciprofloxacin-HCl from a reservoir-based, bioresorbable and elastomeric device. | Tobias, IS., et al. 2010. J Control Release. 146: 356-62. PMID: 20566343
- Preparation and characterizations of silver incorporated polyurethane composite nanofibers via electrospinning for biomedical applications. | Nirmala, R., et al. 2013. J Nanosci Nanotechnol. 13: 4686-93. PMID: 23901491
- Ciprofloxacin HCl-loaded calcium carbonate nanoparticles: preparation, solid state characterization, and evaluation of antimicrobial effect against Staphylococcus aureus. | Maleki Dizaj, S., et al. 2017. Artif Cells Nanomed Biotechnol. 45: 535-543. PMID: 27012878
- Acetic and Acrylic Acid Molecular Imprinted Model Silicone Hydrogel Materials for Ciprofloxacin-HCl Delivery. | Hui, A., et al. 2012. Materials (Basel). 5: 85-107. PMID: 28817033
- The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro. | Wolfson, JS. and Hooper, DC. 1985. Antimicrob Agents Chemother. 28: 581-6. PMID: 3000292
- Enhanced antibacterial activity of Egyptian local insects' chitosan-based nanoparticles loaded with ciprofloxacin-HCl. | Marei, N., et al. 2019. Int J Biol Macromol. 126: 262-272. PMID: 30584935
- Ciprofloxacin HCl and quercetin functionalized electrospun nanofiber membrane: fabrication and its evaluation in full thickness wound healing. | Ajmal, G., et al. 2019. Artif Cells Nanomed Biotechnol. 47: 228-240. PMID: 30688107
- A safe and efficient method for elimination of cell culture mycoplasmas using ciprofloxacin. | Schmitt, K., et al. 1988. J Immunol Methods. 109: 17-25. PMID: 3282011
- Two Validated Chromatographic Methods for Determination of Ciprofloxacin HCl, One of its Specified Impurities and Fluocinolone Acetonide in Newly Approved Otic Solution. | Tantawy, MA., et al. 2022. J Chromatogr Sci. 60: 655-662. PMID: 34545393
- Development and Optimization of Ciprofloxacin HCl-Loaded Chitosan Nanoparticles Using Box-Behnken Experimental Design. | Soliman, NM., et al. 2022. Molecules. 27: PMID: 35889340
Inhibitor of:
Topo II.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ciprofloxacin HCl, 1 g | sc-29064 | 1 g | $84.00 | |||
Ciprofloxacin HCl, 5 g | sc-29064A | 5 g | $180.00 |