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Na+/K+-ATPase α (H-300) Antibody: sc-28800

 |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 551-850 mapping within an internal region of Na+/K+-ATPase α1 of human origin
  • recommended for detection of Na+/K+-ATPase α1, 2 and 3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
 
Additional Sodium/Potassium-ATPase Protein Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
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WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ATP1A1 476 1p13.1 NM_000701, NM_001001586 P05023
182310
Mouse Atp1a1 11928 3 F2.2 Q8VDN2
N/A
Mouse 27222
N/A
Mouse Atp1a2 98660 1 H3 Q6PIE5
N/A
Mouse Atp12a 192113 14 C3 Q9Z1W8
N/A
Mouse Atp1a3 232975 7 A3 Q6PIC6
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Na+/K+-ATPase α (H-300) sc-28800 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Na+/K+-ATPase α siRNA (h) sc-43956 10 µM $258
Na+/K+-ATPase α (h)-PR sc-43956-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Na+/K+-ATPase α shRNA Plasmid (h) sc-43956-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Na+/K+-ATPase α shRNA (h) Lentiviral Particles sc-43956-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Caki-1 Cell Lysate sc-2224 500 µg/200 µl $104
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104

Na+/K+-ATPase α Background Information
The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, å, ∫ and ©, comprise the Na+/K+-ATPase oligomer. The å subunit contains the binding sites for ATP and the cations; the glycosylated ∫ subunit ensures correct folding and membrane insertion of the å subunits. The small © subunit co-localizes with the å subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The ∫ subunit, but not the © subunit, is essential for normal activity of Na+/K+-ATPase.

Na+/K+-ATPase α (H-300) Product Citations
See how others have used Na+/K+-ATPase α (H-300): sc-28800 antibody and or Na+/K+-ATPase α (H-300) antibody conjugates.


14 total citations
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Na+/K+-ATPase α (H-300)
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Na+/K+-ATPase α (H-300): sc-28800. Western blot analysis of Na+/K+-ATPase α expression in HeLa (A) and Caki-1 (B) whole cell lysates.
Na+/K+-ATPase α (H-300): sc-28800. Immunofluorescence staining of normal mouse heart frozen section showing membrane staining.
Na+/K+-ATPase α (H-300): sc-28800. Western blot analysis of Na+/K+-ATPase α expression in 293T (A) and HeLa (B) whole cell lysates.
Na+/K+-ATPase α (H-300): sc-28800. Western blot analysis of Na+/K+-ATPase α3 expression in Hep G2 whole cell lysate.
Na+/K+-ATPase α (H-300): sc-28800. Western blot analysis of Na+/K+-ATPase α1 expression in non-transfected 293T: sc-117752 (A), human Na+/K+-ATPase α1 transfected 293T: sc-116148 (B) and HeLa (C) whole cell lysates.
Na+/K+-ATPase α (H-300): sc-28800. Western blot analysis of Na+/K+-ATPase α1 expression in non-transfected 293T: sc-117752 (A), mouse NNa+/K+-ATPase α1 transfected 293T: sc-121918 (B) and HeLa (C) whole cell lysates.
Na+/K+-ATPase α (H-300): sc-28800. Western blot analysis of Na+/K+-ATPase α1 expression in non-transfected 293T: sc-117752 (A), mouse Na+/K+-ATPase α1 transfected 293T: sc-121919 (B) and HeLa (C) whole cell lysates.
Na+/K+-ATPase α (H-300): sc-28800. Western blot analysis of Na+/K+-ATPase α2 expression in non-transfected 293T: sc-117752 (A), mouse Na+/K+-ATPase α2 transfected 293T: sc-121927 (B), HeLa (C) and NIH/3T3 (D) whole cell lysates.
Na+/K+-ATPase α3 (H-300): sc-28800. Western blot analysis of Na+/K+-ATPase α3 expression in non-transfected 293: sc-110760 (A), human Na+/K+-ATPase α3 transfected 293: sc-158752 (B) and THP-1 (C) whole cell lysates.
Na+/K+-ATPase α (H-300): sc-28800. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing membrane and cytoplasmic staining of glandular cells.
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