santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Transcription Regulators » RBP-J kappa Antibody / RBP-J kappa Antibodies » RBP-Jκ (H-50): sc-28713

RBP-Jκ (H-50) Antibody: sc-28713

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 451-500 mapping at the C-terminus of RBP-Jκ of human origin
  • recommended for detection of RBP-Jκ of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-28713 X, 200 µg/0.1 ml
 
Additional RBP-J kappa Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RBPJ 3516 4p15.2 NM_005349, NM_015874, NM_203283, NM_203284 Q06330
 147183
Mouse Rbpj 19664 5 C1 P31266
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
RBP-Jκ (H-50) sc-28713 200 µg/ml $279
RBP-Jκ (H-50) X sc-28713 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RBP-Jκ siRNA (h) sc-38214 10 µM $258
RBP-Jκ siRNA (m) sc-38215 10 µM $258
RBP-Jκ siRNA (h) sc-38214-PR 10 µM $23
RBP-Jκ siRNA (m) sc-38215-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RBP-Jκ shRNA Plasmid (h) sc-38214-SH 20 µg $520
RBP-Jκ shRNA Plasmid (m) sc-38215-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RBP-Jκ shRNA (h) Lentiviral Particles sc-38214-V 200 µl $625
RBP-Jκ shRNA (m) Lentiviral Particles sc-38215-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RBP-Jκ (h3): 293T Lysate sc-177851 100µg/200µl $205
RBP-Jκ (h2): 293T Lysate sc-117065 100µg/200µl $205
RBP-Jκ (m): 293T Lysate sc-123024 100µg/200µl $205
NIH/3T3 nuclear extract sc-2138 1000 µg $143
HeLa nuclear extract sc-2120 1000 µg $143
Ramos nuclear extract sc-2153 1000 µg $143
BJAB nuclear extract sc-2145 1000 µg $143

RBP-Jκ Background Information
Recombination signal binding protein J˚ (RBP-J˚), also designated KBF2 or CBF1, is the mammalian homolog of the Drosophila Suppressor of Hairless [Su(H)], a protein involved in the development of the peripheral nervous system. RBP-J˚ is ubiquitously expressed in mammalian tissues and is involved in the regulation of gene expression. RBP-J˚ has been shown to directly interact with the intercellular domain of the cell surface receptor Notch 1. Proteolytically cleaved Notch 1 translocates to the nucleus, where it binds DNA-bound RBP-J˚ and activates transcription of target genes. These genes include NF˚B p52 and the Epstein-Barr virus (EBV) protein EBNA-2, both of which contain RBP-J˚-binding sequences within their promoter regions.

RBP-Jκ (H-50) Product Citations
See how others have used RBP-Jκ (H-50): sc-28713 antibody and or RBP-Jκ (H-50) antibody conjugates.


6 total citations
Loading citations.
 
RBP-Jκ (H-50)
Click on image to enlarge
sc-28713
RBP-Jκ (H-50): sc-28713. Western blot analysis of RBP-Jκ expression in non-transfected: sc-117752 (A) and human RBP-Jκ transfected: sc-177851 (B) 293T whole cell lysates.
Download
Datasheets
Get Adobe Acrobat Reader