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home » Transcription Regulators » CLIM Antibody / CLIM Antibodies » CLIM-1/2 (H-300): sc-28695

CLIM-1/2 (H-300) Antibody: sc-28695

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 1-300 of CLIM-1 of human origin
  • recommended for detection of CLIM-1 and CLIM-2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine and avian
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-28695 X, 200 µg/0.1 ml
 
Additional CLIM Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human LDB1 8861 10q24.32 NM_003893 Q86U70
 603451
Mouse Ldb1 16825 19 C3 P70662
 N/A
Mouse Ldb2 16826 5 B3 O55203
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CLIM-1/2 (H-300) sc-28695 200 µg/ml $279
CLIM-1/2 (H-300) X sc-28695 X 200 µg/0.1 ml $279
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CCRF-CEM nuclear extract sc-2146 1000 µg $143
CLIM-2 (h): 293 Lysate sc-176386 100µg/200µl $205
CLIM-2 (m): 293T Lysate sc-119307 100µg/200µl $205
CCRF-CEM Cell Lysate sc-2225 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
HeLa nuclear extract sc-2120 1000 µg $143

CLIM-1/2 Background Information
CLIM-1/2 (LIM domain-binding factor-2, LDB1,CLP36, ELFIN, CLP-36, enigma homolog) is a LIM domain-containing protein. LIM domain-containing proteins are capable of binding to a variety of transcription factors. They are likely to function as enhancers, to bring together diverse transcription factors and form higher order activation complexes, or to block formation of such complexes. Human CLIM-1 is a cytoplasmic protein. CLIM-1 northern blot analysis reveals expression of an approximately 2.0-kb transcript most abundant in heart and skeletal muscle. CLIM-1 interacts with the C-terminal EF hand region of alpha-actinin-2 through a LIM domain. CLIM-1 localizes to actin stress fibers in nonmuscle cells and associates with alpha-actinin via its PDZ-domain.

CLIM-1/2 (H-300)
Click on image to enlarge
sc-28695
CLIM-1/2 (H-300): sc-28695. Western blot analysis of CLIM-1 and CLIM-2 expression in CCRF-CEM nuclear extract.
sc-28695
CLIM-1/2 (H-300): sc-28695. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing nuclear staining of cells in granular and molecular layers and Purkinje cells (low and high magnification). Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-28695
CLIM-1/2 (H-300): sc-28695. Western blot analysis of CLIM-2 expression in non-transfected 293T: sc-117752 (A), mouse CLIM-2 transfected 293T: sc-119307 (B) and CCRF-CEM (C) whole cell lysates.
sc-28695
CLIM-1/2 (H-300): sc-28695. Western blot analysis of CLIM-2 expression in HeLa whole cell lysate.
sc-28695
CLIM-1/2 (H-300): sc-28695. Western blot analysis of CLIM-1/2 expression in HeLa nuclear extract.
sc-28695
CLIM-1/2 (H-300): sc-28695. Western blot analysis of CLIM-2 expression in non-transfected: sc-110760 (A) and human CLIM-2 transfected: sc-176386 (B) 293 whole cell lysates and HeLa nuclear extract (C).
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