Welcome to Santa Cruz Biotechnology!

AQP2 Antibody (H-40): sc-28629

 |  Datasheet

(Based on data analysis)

  • AQP2 Antibody (H-40) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 232-271 mapping within a C-terminal cytoplasmic domain of AQP2 of human origin
  • recommended for detection of AQP2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • See 5 citations for AQP2 Antibody (H-40)
 
Full-length AQP2 protein sequence with immunogen highlighted:
MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGTKA

See additional AQP Antibodies including AQP, AQP0, AQP1, AQP12A, AQP2, AQP3, AQP4, AQP5, AQP6, AQP7, AQP8, AQP9, AQP10 and AQP11.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
AQP2 Antibody (H-40) sc-28629 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AQP2 siRNA (h) sc-42363 10 µM $258
AQP2 siRNA (m) sc-42364 10 µM $258
AQP2 (h)-PR sc-42363-PR 10 µM, 20 µl $23
AQP2 (m)-PR sc-42364-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AQP2 shRNA Plasmid (h) sc-42363-SH 20 µg $520
AQP2 shRNA Plasmid (m) sc-42364-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AQP2 shRNA (h) Lentiviral Particles sc-42363-V 200 µl $625
AQP2 shRNA (m) Lentiviral Particles sc-42364-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Caki-1 Cell Lysate sc-2224 500 µg/200 µl $104
COLO 320DM Cell Lysate sc-2226 500 µg/200 µl $104
rat kidney extract sc-2394 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human AQP2 359 12q13.13 NM_000486 P41181
125800
Mouse Aqp2 11827 15 F1 P56402
N/A
 


Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.

AQP2 Antibody (H-40) Product Citations
See how others have used AQP2 Antibody (H-40) and or AQP2 Antibody (H-40) conjugates.


5 total citations
Loading citations.
 
AQP2 Antibody (H-40) Data
Click on image to enlarge
AQP2 (H-40): sc-28629. Western blot analysis of AQP2 expression in Caki-1 (A) and COLO 320DM (B) whole cell lysates.
AQP2 (H-40): sc-28629. Immunoperoxidase staining of formalin fixed, paraffin-embedded human renal cancer tissue showing perinuclear and cytoplasmic staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
AQP2 (H-40): sc-28629. Western blot analysis of human recombinant AQP2 fusion protein.
Download