Tns Background Information Tensin (Tns) is an actin filament capping protein localized to various types of adherens junctions in muscle and non-muscle cells. Tensin is involved in the maintenance of cellular structure by anchoring actin filaments at the focal adhesion via F-actin binding and capping activities. However, tensin also contains a Src homology 2 (SH2) domain and has the ability to be phosphorylated. Tensin is phosphorylated on tyrosine, serine and threonine residues, suggesting that it might participate in signal transduction cascades. These diverse characteristics in a single molecule indicate that tensin may be an important link between the cytoskeleton and signal transduction pathways.
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Tns (H-300)
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Tns (H-300): sc-28542. Western blot analysis of Tns expression in A-10 whole cell lysate.
Tns (H-300): sc-28542. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing basement membrane and cytoplasmic staining of cells in glomeruli and tubules at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Tns (H-300): sc-28542. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing basement membrane and cytoplasmic staining of cells in glomeruli and tubules at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Tns (H-300): sc-28542. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
