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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of CDY of human origin
- recommended for detection of CDY isoforms 1 and 2, and CDYL of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-28468 P
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Ordering Information
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CDY Background Information
CDY, a gene family expressed exclusively in the testis, localizes to a region of the Y chromosome frequently deleted in infertile males. CDY protein contains two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and also a C-terminal domain which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY acts as a histone acetyltransferase, with strong preference for histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. |
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CDY (C-16)
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CDY (C-16): sc-28468. Western blot analysis of CDY expression in F9 (A) and AMJ2-C11 (B) whole cell lysates.
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