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home » Transcription Regulators » HEB Antibody / HEB Antibodies » HEB (D-3): sc-28364

HEB (D-3) Antibody: sc-28364

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • raised against amino acids 31-160 of HEB of human origin
  • recommended for detection of HEB of human origin by WB, IP, IF, IHC(P) and ELISA
 
Additional HEB Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TCF12 6938 15q21.3 NM_003205, NM_207036, NM_207037, NM_207038, NM_207040 Q99081
 600480
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
HEB (D-3) sc-28364 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HEB siRNA (h) sc-35552 10 µM $258
HEB (h)-PR sc-35552-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HEB shRNA Plasmid (h) sc-35552-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HEB shRNA (h) Lentiviral Particles sc-35552-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Jurkat nuclear extract sc-2132 1000 µg $143
SJRH30 Cell Lysate sc-2287 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
SW480 Cell Lysate sc-2219 500 µg/200 µl $104

HEB Background Information
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.

HEB (D-3)
Click on image to enlarge
sc-28364
HEB (D-3): sc-28364. Western blot analysis of HEB expression in Jurkat nuclear extract (A) and SJRH30 whole cell lysate (B).
sc-28364
HEB (D-3): sc-28364. Immunofluorescence staining of methanol-fixed Jurkat cells showing nuclear localization.
sc-28364
HEB (D-3): sc-28364. Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing nuclear staining of surface epithelial cells (low and high magni?fication). Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-28364
HEB (D-3): sc-28364. Western blot analysis of HEB expression in non-transfected 293T: sc-117752 (A), human HEB transfected 293T: sc-116193 (B) and Jurkat (C) whole cell lysates.
sc-28364
HEB (D-3): sc-28364. Western blot analysis of HEB expression in non-transfected: sc-117752 (A) and human HEB transfected: sc-177333 (B) 293T whole cell lysates and Jurkat nuclear extract (C).
sc-28364
HEB (D-3): sc-28364. Western blot analysis of HEB expression in non-transfected: sc-117752 (A) and human HEB transfected: sc-177334 (B) 293T whole cell lysates and Jurkat nuclear extract (C).
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