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Fra-1 (C-12) Antibody: sc-28310

 |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • raised against amino acids 1-50 of Fra-1 of human origin
  • recommended for detection of Fra-1 of h and r origin by WB, IP, IF, IHC(P) and ELISA
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-28310 X, 200 µg/0.1 ml
 
Additional Fra Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human FOSL1 8061 11q13.1 NM_005438 P15407
136515
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Fra-1 (C-12) sc-28310 200 µg/ml $279
Fra-1 (C-12) X sc-28310 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fra-1 siRNA (h) sc-35405 10 µM $258
Fra-1 (h)-PR sc-35405-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fra-1 shRNA Plasmid (h) sc-35405-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fra-1 shRNA (h) Lentiviral Particles sc-35405-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fra-1 (h7): 293T Lysate sc-113305 100µg/200µl $205
U-937 Cell Lysate sc-2239 500 µg/200 µl $104
HeLa nuclear extract sc-2120 1000 µg $143
3611-RF + PMA nuclear extract sc-2144 1000 µg $143
Fra-1 (h): 293T Lysate sc-176608 100µg/200µl $205
Fra-1 (h4): 293T Lysate sc-176740 100µg/200µl $205

Fra-1 Background Information
The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.

Fra-1 (C-12) Product Citations
See how others have used Fra-1 (C-12): sc-28310 antibody and or Fra-1 (C-12) antibody conjugates.


3 total citations
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Fra-1 (C-12)
Click on image to enlarge
Fra-1 (C-12): sc-28310. Western blot analysis of Fra-1 expression in untreated (A) and PMA-induced (B) 3611-RF nuclear extracts.
Fra-1 (C-12): sc-28310. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervical cancer showing nuclear staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Fra-1 (C-12): sc-28310. Western blot analysis of Fra-1 expression in non-transfected: sc-117752 (A) and human Fra-1 transfected: sc-113305 (B) 293T whole cell lysates.
Fra-1 (C-12): sc-28310. Western blot analysis of Fra-1 expression in BJ nuclear extract.
Fra-1 (C-12): sc-28310. Western blot analysis of Fra-1 expression in non-transfected: sc-117752 (A) and human Fra-1 transfected: sc-176608 (B) 293T whole cell lysates.
Fra-1 (C-12): sc-28310. Western blot analysis of Fra-1 expression in non-transfected: sc-117752 (A) and human Fra-1 transfected: sc-176740 (B) 293T whole cell lysates.
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