epitope corresponding to amino acids 1-45 mapping at the N-terminus of galectin-1 of human origin
recommended for detection of galectin-1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, bovine and porcine
galectin-1 Background Information Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Specifically, Galectin-1 is an autocrine regulator of cell-proliferation that plays a role in the maintenance of G0 and in the control of G2 traverse. Galectin-1, also known as LGALS1, is the protein product of a single gene linked to human chromosome 22q13.1. The Galectin-1 protein contains 135 amino acids, a single internal EcoRI site and a polyadenylation signal. Galectin-1 can localize to both intracellular and extracellular space. Galectin-1 is expressed in human placenta, human lung, HL-6, HepG2 and CEM cells.
galectin-1 (H-45) Product Citations
See how others have used galectin-1 (H-45): sc-28248 antibody and or galectin-1 (H-45) antibody conjugates.
6 total citations
Loading citations.
galectin-1 (H-45)
Click on image to enlarge
galectin-1 (H-45): sc-28248. Western blot analysis of galectin-1 expression in HL-60 (A) and SK-MEL-28 (B) whole cell lysates.
galectin-1 (H-45): sc-28248. Western blot analysis of galectin-1 expression in non-transfected: sc-117752 (A) and mouse galectin-1 transfected: sc-120390 (B) 293T whole cell lysates.
galectin-1 (H-45): sc-28248. Western blot analysis of galectin-1 expression in HL-60 (A) and NIH/3T3 (B) whole cell lysates.
galectin-1 (H-45): sc-28248. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and membrane localization.
