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home » Tumor Suppressors/Apoptosis » NRAGE Antibody / NRAGE Antibodies » NRAGE (H-300): sc-28243

NRAGE (H-300) Antibody: sc-28243

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 1-300 mapping at the N-terminus of NRAGE of human origin
  • recommended for detection of NRAGE of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
 
Additional NRAGE Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MAGED1 9500 Xp11.22 NM_001005332, NM_001005333, NM_006986 Q9Y5V3
 300224
Mouse Maged1 94275 X C3 Q9QYH6
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
NRAGE (H-300) sc-28243 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NRAGE siRNA (h) sc-37320 10 µM $258
NRAGE siRNA (m) sc-45975 10 µM $258
NRAGE (h)-PR sc-37320-PR 10 µM $23
NRAGE (m)-PR sc-45975-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NRAGE shRNA Plasmid (h) sc-37320-SH 20 µg $520
NRAGE shRNA Plasmid (m) sc-45975-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NRAGE shRNA (h) Lentiviral Particles sc-37320-V 200 µl $625
NRAGE shRNA (m) Lentiviral Particles sc-45975-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NRAGE (h): 293T Lysate sc-114826 100µg/200µl $205
mouse brain extract sc-2253 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104

NRAGE Background Information
The neurotrophin family of growth factors (NGF) function to regulate neuronal differentiation, synaptic activity and neuronal survival, as well as axonal and dendritic growth. The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. Neurotrophin receptor-interacting MAGE homolog (NRAGE) binds the p75 neurotrophin re-ceptor and associates with the plasma membrane when NGF binds p75NTR. The critical factors for NRAGE association lie within the juxtamembrane domain of p75NTR. Overexpression of NRAGE stimulates cell cycle arrest and allows NGF-dependent apoptosis within sympathetic neuron precursors cells. NRAGE is expressed in the medulla oblongata during development and motor-neurons. Structural similarities suggest NRAGE, and the MAGE protein necdin, (Ndn), mediate cell cycle effects through a shared mechanism.
NRAGE (H-300)
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sc-28243
NRAGE (H-300): sc-28243. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
sc-28243
NRAGE (H-300): sc-28243. Western blot analysis of NRAGE expression in non-transfected: sc-117752 (A) and human NRAGE transfected: sc-114826 (B) 293T whole cell lysates.
sc-28243
NRAGE (H-300): sc-28243. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing cytoplasmic staining of adnexal and epidermal cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-28243
NRAGE (H-300): sc-28243. Western blot analysis of NRAGE expression in mouse brain tissue extract.
sc-28243
NRAGE (H-300): sc-28243. Western blot analysis of NRAGE expression in mouse brain tissue extract.
sc-28243
NRAGE (H-300): sc-28243. Western blot analysis of NRAGE expression in non-transfected 293T: sc-117752 (A), mouse NRAGE transfected 293T: sc-122121 (B), Jurkat (C) and ALL-S1L (D) whole cell lysates.
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