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DMBT1 Antibody (H-130): sc-28239

 |  Datasheet

(Based on data analysis)

  • DMBT1 Antibody (H-130) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1516-1645 mapping near the C-terminus of DMBT1 of human origin
  • recommended for detection of DMBT1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
 

See additional DMBT1 Antibodies.

Ordering InformationGene Info
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WB   IP   IF   IHC(P)   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
DMBT1 Antibody (H-130) sc-28239 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DMBT1 siRNA (h) sc-35196 10 µM $258
DMBT1 siRNA (m) sc-35197 10 µM $258
DMBT1 (h)-PR sc-35196-PR 10 µM, 20 µl $23
DMBT1 (m)-PR sc-35197-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DMBT1 shRNA Plasmid (h) sc-35196-SH 20 µg $520
DMBT1 shRNA Plasmid (m) sc-35197-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DMBT1 shRNA (h) Lentiviral Particles sc-35196-V 200 µl $625
DMBT1 shRNA (m) Lentiviral Particles sc-35197-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human DMBT1 1755 10q26.13 NM_004406, NM_007329, NM_017579 Q9UGM3
 601969
Mouse Dmbt1 12945 7 F3 Q60997
 N/A
 

As human tumors progress to advanced stages, one genetic alteration that occurs at high frequency is a loss of heterozygosity (LOH) at chromosome 10. Mapping of homozygous deletions on this chromosome led to the isolation of the PTEN (also designated MMAC1 and TEP1), DMBT1 (for deleted in malignant brain tumors 1) and LGI1 (for leucine-rich gene-glioma inactivated 1) candidate tumor suppressor genes. The PTEN gene exhibits a high frequency of mutations in human glioblastomas and is also mutated in other cancers, including sporadic brain, breast, kidney and prostate cancers. Reduced levels of DMBT1 mRNA have been noted in gastrointestinal and esophageal cancers as well as in gliomas. LGI1, which is highly specific for neural tissues, shares homology with several transmembrane and extracellular proteins that function as receptors and adhesion proteins.
DMBT1 Antibody (H-130) Data
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sc-28239
DMBT1 (H-130): sc-28239. Immunoperoxidase staining of formalin fixed, paraffin-embedded human epididymis tissue showing cytoplasmic staining of glandular cells.
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