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CYP11B1/2 Antibody (H-300): sc-28205

 |  Datasheet

(Based on data analysis)

  • CYP11B1/2 Antibody (H-300) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 204-503 (deletion 401-466) mapping at the C-terminus of CYP11B1 of human origin
  • recommended for detection of CYP11B1 and CYP11B2 of human origin by WB, IP, IF and ELISA
 

See additional CYP Antibodies including CYP, CyP, Cyp21a1, CYP27C1, CYP2A12, CYP2A13, CYP2A22, CYP2A4, CYP2A5, CYP2A7, CYP2AB1, CYP2B10, CYP2B123, CYP2B13, CYP2B19, CYP2B9, Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c40, Cyp2c44, Cyp2c50, Cyp2c54, Cyp2c55, Cyp2c65, Cyp2c66, Cyp2c67, Cyp2c68, Cyp2c69, Cyp2c70, CYP2D10, CYP2D11, CYP2D12, CYP2D22, CYP2D26, CYP2D34, CYP2D40, CYP2D9, CYP2G1, CYP2J11, CYP2J12, CYP2J13, CYP2J5, CYP2J7, CYP2J8, CYP2J9, CYP2T4, Cyp3a11, Cyp3a13, Cyp3a16, Cyp3a25, Cyp3a41a, Cyp3a41b, CYP3A43, Cyp3a44, Cyp3a57, Cyp3a59, CYP4A12A, CYP4A12B, CYP4A29, CYP4A30B, CYP4F12, Cyp4f13, Cyp4f14, Cyp4f15, Cyp4f16, Cyp4f17, CYP4F22, CYP4F3, Cyp4f37, Cyp4f39, Cyp4f40, CYP4F43P, CYP4F8, CYP4V3, CYP51A1, CYP2A, CYP3A, CYP4A, CYP11B, CYP1A1, CYP1B1, CYP1A2, CYP19, CYP2B1, CYP2E1, CYP2F1, CYP2R1, CYP2S1, CYP2U1, CYP2W1, CYP2B2, CYP2F2, CYP2J2, CYP24, CYP26A1, CYP2A6, CYP2B6, CYP2C6, CYP2D6, CYP2J6, CYP2C8, CYP2C9, CYP3A1, CYP3A4, CYP3A5, CYP3A7, CYP4A1, CYP4B1, CYP4X1, CYP4Z1, CYP4A2, CYP4F2, CYP4V2, CYP4A3, CYP46, CYP7A1, CYP7B1, CYP8B1, CYP11A1, CYP11B1, CYP17A1, CYP20A1, CYP21A2, CYP2C18, CYP2C19, CYP27A1, CYP27B1, CYP39A1, CYP4A10, CYP4A11, CYP4F11, CYP4A14, CYP4A22, CYP4A31 and CYP4A32.

Also see CYP Inhibitors, CYP Activators or CYP Substrates for functional analysis of cellular responses to CYP.


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Product NameCatalog #UnitPriceQtyAdd 
CYP11B1/2 Antibody (H-300) sc-28205 200 µg/ml $279


The steroid 11beta-hydroxylase gene, also designated Cyp11b-1, is a marker for the functional differentiation of cells in the zonae fasciculata reticularis. The deduced protein CYP11B1 consists of 466 amino acids containing a secretory signal, epidermal growth factor-like repeats, and a proteolytically inactive cathepsin B-related sequence. A related protein, human aldosterone synthase (CYP11B2), is involved in substrate recognition and conversion, with a functionally significant residue 112 in the N-terminal region of human CYP11B2. The inherited disorder glucocorticoid-remediable aldosteronism iscaused by a chimeric gene duplication between the CYP11B1 and CYP11B2 genes. This disorder is characterized by hyperaldosteronism and high levels of 18-hydroxycortisol and 18-oxocortisol, which are under ACTH control.

CYP11B1/2 Antibody (H-300) Data
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CYP11B1/2 (H-300): sc-28205. Western blot analysis of CYP11B1/2 expression in rat adrenal gland tissue extract.
CYP11B1/2 (H-300): sc-28205. Western blot analysis of CYP11B1/2 expression in MCF7 whole cell lysate.
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