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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 21-150 of BTEB1 of human origin
- recommended for detection of BTEB1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
KLF9 |
687 |
9q21.11 |
NM_001206 |
Q13886
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602902 |
| Mouse |
Klf9 |
16601 |
19 B |
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O35739
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N/A |
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BTEB1 Background Information
Members of the C2H2 zinc finger family bind GC-rich motifs widely distributed in gene promoters, resulting in distinct activation or repression of transcriptional activities (1,2). In addition to Sp1, Sp2, Sp3, and Sp4, the basic transcription element binding proteins-1 and -2 (BTEB1 and BTEB2, respectively), belong to this family of transcriptional regulators (1,3). BTEB1 regulates transcription by binding either a single GC-box or tandemly repeated GC-boxes within the promoter (2). Predominantly localized to the nuclei of endometrial luminal and glandular epithelial cells, BTEB1 expression is both acetaldehyde and UV inducible (1,4,5). BTEB1 plays a regulatory role in pregnancy-associated endometrial epithelial gene expression and also mediates JNK-dependent alpha (I) collagen gene expression in hepatic stellate cells (5). |
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BTEB1 (H-130)
Click on image to enlarge
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BTEB1 (H-130): sc-28195. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
BTEB1 (H-130): sc-28195. Western blot analysis of BTEB1 expression in IMR-32 nuclear extract.
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