Zic2 Background Information Zic2 (zinc finger protein of the cerebellum 2) is a C2H2 zinc finger transcription factor that influences forebrain development. Zic2 is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Zic2 transcript is abundant in the dorsal neural tube/spinal cord, and in the hindbrain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Zic2 (C-14)
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Zic2 (C-14): sc-28153. Western blot analysis of Zic2 expression in NIH/3T3 nuclear extract.