epitope mapping within an internal region of Zic2 of human origin
recommended for detection of Zic2 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
blocking peptide, sc-28152 P
TransCruz reagent for Gel Supershift and ChIP applications, sc-28152 X, 200 µg/0.1 ml
Zic2 Background Information Zic2 (zinc finger protein of the cerebellum 2) is a C2H2 zinc finger transcription factor that influences forebrain development. Zic2 is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Zic2 transcript is abundant in the dorsal neural tube/spinal cord, and in the hindbrain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.