Ticarcillin/Clavulanate (15/1) (CAS 4697-14-7)

Ticarcillin/Clavulanate (15/1) is a combination antibiotic that consists of ticarcillin and clavulanate in a fixed ratio of 15 to 1. It represents a potent combination utilized primarily in the realm of microbiological research to investigate bacterial resistance mechanisms and the efficacy of antibiotic regimens. Ticarcillin, a broad-spectrum penicillin antibiotic, operates by inhibiting the synthesis of peptidoglycan, a critical component of bacterial cell walls, leading to cell lysis and bacterial death. Clavulanate, on the other hand, acts as a β-lactamase inhibitor, protecting ticarcillin from enzymatic degradation by β-lactamase-producing bacteria. This synergistic interaction enhances the spectrum of ticarcillin′s antibacterial activity, making the combination particularly valuable for studying antibiotic resistance patterns and the development of strategies to overcome them. This combination is instrumental in elucidating the dynamics of bacterial survival mechanisms, thereby contributing to the advancement of research in microbial pathogenicity and the search for novel antimicrobial agents.