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home » Cell Cycle Proteins » BRD Antibody / BRD Antibodies » BRD4 (K-14): sc-27976

BRD4 (K-14) Antibody: sc-27976

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the C-terminus of Bromodomain-containing protein 4 of human origin
  • recommended for detection of BRD4 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and porcine
  • blocking peptide, sc-27976 P
 
Additional BRD Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human BRD4 23476 19p13.12 NM_014299, NM_058243 O60885
 608749
Mouse Brd4 57261 17 B1 Q9ESU6
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
BRD4 (K-14) sc-27976 200 µg/ml $279
Brd4 (K-14) P sc-27976 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
BRD4 siRNA (h) sc-43639 10 µM $258
BRD4 siRNA (m) sc-141740 10 µM $258
Brd4 (h)-PR sc-43639-PR 10 µM $23
BRD4 (m)-PR sc-141740-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Brd4 shRNA Plasmid (h) sc-43639-SH 20 µg $520
BRD4 shRNA Plasmid (m) sc-141740-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Brd4 shRNA (h) Lentiviral Particles sc-43639-V 200 µl $625
BRD4 shRNA (m) Lentiviral Particles sc-141740-V 200 µl $625

BRD4 Background Information
Brd4 belongs to the BET family, a group of structurally related proteins containing two bromodomains. Through these two domains, Brd4 associates with mitotic chromosomes and its expression correlates with cell growth. Expression of Brd4 inhibits cell cycle progression from G(1) to S, due to binding to the largest subunit of replication factor C (RFC) to prevent DNA elongation. Altered Brd4 function correlates with poorly differentiated carcinoma, with aggresive phenotype and a highly lethal outcome.
BRD4 (K-14)
Click on image to enlarge
sc-27976
BRD4 (K-14): sc-27976. Western blot analysis of BRD4 expression in human PBL whole cell lysate.
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Datasheets
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