epitope mapping at the C-terminus of MDC1 of human origin
recommended for detection of MDC1 of human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
MDC1 Background Information MDC1, also designated nuclear factor with BRCT domains protein 1 (NFBD1), participates in the early response to DNA damage. It is involved in promoting recruitment of repair proteins to the site of DNA breaks and controls damage-induced cell-cycle arrest checkpoints. The nuclear protein is a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.
MDC1 (C-20) Product Citations
See how others have used MDC1 (C-20): sc-27737 antibody and or MDC1 (C-20) antibody conjugates.