RIN4 Background Information Bacterial pathogens deliver type III effector proteins into the plant cell during infection. Plants express disease resistance (R) proteins that respond specifically to a particular type III effector by activating immune responses. RPM1-interacting protein 4 (RIN4) associates with Resistance to Pseudomonas syringae pv maculicola 1 (RPM1) and Resistance to P. syringae 2 (RPS2) disease resistance proteins. RIN4 is the host target for AvrRpm1 and AvrRpt2 in susceptible plants. RIN4 negatively regulates AvrRpt2 virulence function. RIN4 also negatively regulates inappropriate activation of both RPM1 and RPS2.
