Date published: 2025-10-26

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IDE Antibodies

Santa Cruz Biotechnology features a diverse variety of IDE Antibodies for advanced research in protein function and regulation. Monoclonal IDE Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Insulin-degrading enzyme (IDE) plays a crucial role in the metabolism of insulin and amyloid-beta peptides, making it significant in diabetes and Alzheimer's disease research. By regulating peptide levels, IDE contributes to maintaining glucose homeostasis and preventing toxic aggregate accumulation in the brain. Understanding IDE function is essential for developing therapeutic strategies targeting metabolic disorders and neurodegenerative diseases. Research has shown that IDE activity influences both insulin signaling pathways and amyloid-beta clearance mechanisms. Recent studies have highlighted IDE's potential as a therapeutic target for multiple pathological conditions. Investigating IDE's molecular interactions and regulatory mechanisms can provide valuable insights into disease progression and treatment approaches. IDE research using Santa Cruz Biotechnology monoclonal antibodies continues to advance scientific understanding of metabolic and neurodegenerative disorders, supporting breakthrough discoveries in medical research.

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IDE Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IDE Antibody (F-9)

sc-393887mouse IgG1 κ122-145 (h)WB, IP, IF, ELISAm, r, h
29
(9)

IDE Antibody (E-4)

sc-514458mouse IgG1 κ720-1019 (h)WB, IP, IF, ELISAm, r, h
4
(1)

IdeE Antibody (A-9)

sc-390337mouse IgG1 κFL (Streptococcus equi subsp. zooepidemicus)WB, IP, IF, ELISAS. equi

new

(1)

IdeE Antibody (B-1)

sc-390308mouse IgG2a κFL (Streptococcus equi subsp. zooepidemicus)WB, IP, IF, ELISAStreptococcus equi

new

(1)

IdeE2 Antibody (C-1)

sc-514333mouse IgG1 κFL (Streptococcus equi subsp. equi)WB, IP, IF, ELISAStreptococcus equi

new

(1)

IDE CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IDE CRISPR/Cas9 KO Plasmid (h)

sc-401900hGene KnockoutGFP0
(0)

IDE HDR Plasmid (h)

sc-401900-HDRhHomology Directed RepairPuromycin0
(0)

IDE Double Nickase Plasmid (h)

sc-401900-NIChGene KnockoutPuromycin0
(0)

IDE Double Nickase Plasmid (h2)

sc-401900-NIC-2hGene KnockoutPuromycin0
(0)

IDE CRISPR/Cas9 KO Plasmid (m)

sc-421021mGene KnockoutGFP0
(0)

IDE HDR Plasmid (m)

sc-421021-HDRmHomology Directed RepairPuromycin0
(0)

IDE Double Nickase Plasmid (m)

sc-421021-NICmGene KnockoutPuromycin0
(0)

IDE Double Nickase Plasmid (m2)

sc-421021-NIC-2mGene KnockoutPuromycin0
(0)

IDE CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IDE CRISPR Activation Plasmid (h)

sc-401900-ACThGene ActivationPuro, Blast, Hygro0
(0)

IDE CRISPR Activation Plasmid (h2)

sc-401900-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IDE Lentiviral Activation Particles (h)

sc-401900-LAChGene ActivationPuro, Blast, Hygro0
(0)

IDE Lentiviral Activation Particles (h2)

sc-401900-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IDE CRISPR Activation Plasmid (m)

sc-421021-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IDE CRISPR Activation Plasmid (m2)

sc-421021-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IDE Lentiviral Activation Particles (m)

sc-421021-LACmGene ActivationPuro, Blast, Hygro0
(0)

IDE Lentiviral Activation Particles (m2)

sc-421021-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IDE siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IDE siRNA (h)

sc-106817hGene SilencingN/A
1
(0)

IDE shRNA Plasmid (h)

sc-106817-SHhGene SilencingPuromycin
1
(0)

IDE shRNA (h) Lentiviral Particles

sc-106817-VhGene SilencingPuromycin
1
(0)

IDE siRNA (m)

sc-146140mGene SilencingN/A
1
(0)

IDE shRNA Plasmid (m)

sc-146140-SHmGene SilencingPuromycin
1
(0)

IDE shRNA (m) Lentiviral Particles

sc-146140-VmGene SilencingPuromycin
1
(0)