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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the N-terminus of LDH-A of human origin
- recommended for detection of LDH-A of mouse, rat and human origin by WB, IP, IF and ELISA; non cross-reactive with LDH-B and LDH-C
- blocking peptide, sc-27230 P
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
LDHA |
3939 |
11p15.1 |
NM_005566 |
P00338
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150000 |
| Mouse |
Ldha |
16828 |
7 B4 |
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P06151
|
N/A |
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LDH-A Background Information The lactate dehydrogenase family (LDH) catalyzes the final step of anaerobic glycolysis, the conversion of L-lactate and NAD to pyruvate and NADH. The LDH family consists of three members, LDH-A, LDH-B, and LDH-C, all of which form tetramers consisting four subunits. However, each family member displays a specific tissue distribution pattern with LDH-A and LDH-B predominant in several tissues, specifically LDH-A in muscle and LDH-B in heart, while LDH-C expression is confined to the testis and sperm. LDHs function as powerful markers for germ cell tumors. The genes encoding human LDH-A and LDH-C map to chromosome 11, while the human LDH-B gene maps to chromosome 12. Deficiency in the LDH-A gene is linked to exertional myoglobinuria.
| LDH-A (N-14) Product Citations |
See how others have used LDH-A (N-14): sc-27230 antibody and or LDH-A (N-14) antibody conjugates.
7 total citations Loading citations.
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LDH-A (N-14)
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LDH-A (N-14): sc-27230. Western blot analysis of LDH-A expression in HeLa (A), Y79 (B), MDA-MB-231 (C), C32 (D), ME-180 (E) and Ca Ski (F) whole cell lysates.
LDH-A (N-14): sc-27230. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
LDH-A (N-14): sc-27230. Western blot analysis of LDH-A expression in HeLa (A) and ES-2 (B) whole cell lysates and rat skeletal muscle tissue extract (C).
LDH-A (N-14): sc-27230. Western blot analysis of LDH-A expression in non-transfected 293T: sc-117752 (A), mouse LDH-A transfected 293T: sc-127087 (B) and SK-N-SH (C) whole cell lysates.
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