NFATc4 Antibody (B-2) | Santa Cruz Biotech

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NFATc4 Antibody (B-2): sc-271597	\| Datasheet

5 3 (Based on data analysis) 1

NFATc4 Antibody (B-2) is a mouse monoclonal IgG_2a provided at 200 µg/ml
raised against amino acids 125-198 of NFATc4 of human origin
recommended for detection of NFATc4 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
TransCruz reagent for Gel Supershift and ChIP applications, sc-271597 X, 200 µg/0.1 ml

Full-length NFATc4 protein sequence with immunogen highlighted:

MGAASCEDEELEFKLVFGEEKEAPPLGAGG See more...

MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGAQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFPLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEPPA

See additional NFAT Antibodies including NFAT, NFATc1, NFATc2, NFATc3, NFATc4 and NFAT5.

Ordering InformationGene Info

Recommended Support Products:

(click button of application of choice)

WB IP IF IHC(P)

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
NFATc4 Antibody (B-2)	sc-271597	200 µg/ml	$279
NFATc4 Antibody (B-2) X	sc-271597 X	200 µg/0.1 ml	$279

Species	Gene Name	Gene ID	Chromosome Location	Isoform (mRNA) Accession #	Protein Accession #	OMIM™ Number

Human	NFATC4	4776	14q11.2	NM_001136022, NM_004554	NP_004545	602699
Mouse	Nfatc4	73181	14 C3	NM_001168346, NM_023699	Q8K120	N/A

NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 4) is a member of the nuclear factors of activated T cells DNA-binding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components: a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.

NFATc4 Antibody (B-2) Data

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NFATc4 (B-2): sc-271597. Western blot analysis of NFATc4 expression in non-transfected: sc-117752 (A) and human NFATc4 transfected: sc-116481 (B) 293T whole cell lysates.

NFATc4 (B-2): sc-271597. Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing cytoplasmic staining of squamous epithelial cells.

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NFATc4 Antibody (B-2): sc-271597