GATA3 Antibody (HG3-35): sc-269

GATA-3 Antibody (HG3-35) is a mouse monoclonal IgG1 kappa light chain antibody that detects GATA-3 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry (IHC). GATA-3 monoclonal antibody (HG3-35) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase, phycoerythrin, fluorescein isothiocyanate, and multiple Alexa Fluor® conjugates. GATA-3 plays a crucial role in the development and function of T lymphocytes, acting as a key transcription factor that regulates the expression of genes involved in T cell differentiation and function. GATA-3 expression is vital for the development of the immune system, particularly in the differentiation of helper T cells, which are essential for orchestrating immune responses. GATA-3 is predominantly located in the nucleus, where GATA-3 binds to specific DNA sequences to modulate gene expression, highlighting GATA-3′s importance in cellular signaling pathways. GATA-3 is known to interact with other transcription factors, such as T-bet and RORγt, which further underscores GATA-3′s role in the complex regulatory networks that govern T cell lineage commitment and function. Understanding GATA-3 dynamics and interactions is critical for elucidating the mechanisms underlying immune responses and potential therapeutic targets in immune-related diseases.

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LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-GATA3 Antibody (HG3-35) has 49 citations in a variety of scientific publications.

Primary antibodies like Anti-GATA3 Antibody (HG3-35) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

GATA3 Antibody (HG3-35) Specifications

Alternate Product Name: GATA3

Product Clone Name: HG3-35

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-264

Epitope Target: GATA-3

Epitope Species: human

Product Reactivity/Detection: GATA-3

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 49 citations in various scientific publications

Available Conjugates/Forms for GATA3 Antibody (HG3-35): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin, X: TransCruz Reagent

The preferred GATA3 antibody is GATA3 Antibody (HG3-31): sc-268.