Date published: 2026-7-3

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MMP Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of MMP Antibodies for the study of matrix metalloproteinases. MMP Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Matrix metalloproteinases play a crucial role in the remodeling of the extracellular matrix and are involved in numerous physiological and pathological processes, including tissue repair, inflammation, and cancer metastasis. The regulation of matrix metalloproteinases is vital for maintaining tissue homeostasis. Dysregulation of matrix metalloproteinase activity has been linked to various diseases, including arthritis, cardiovascular conditions, and tumor progression. Understanding matrix metalloproteinase function is essential for developing targeted therapeutic strategies. Research into matrix metalloproteinases continues to reveal new insights into their biological significance and potential clinical applications. MMP monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of disease mechanisms and potential treatments.

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MMP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MMP-1 Antibody (3B6)

sc-21731mouse IgG1366-376 (h)WB, IP, IF, IHC(P), ELISAh
96
(17)

MMP-1 Antibody (SB12e)

sc-58377mouse IgG2bFL (h)WB, IP, IF, ELISAh
26
(6)

MMP-1/8 Antibody (A-7)

sc-137044mouse IgG1 κ100-399 (h)WB, IP, IF, ELISAm, r, h
9
(13)

MMP2 Antibody (2C1)

sc-13594mouse IgG1 κ(h)WB, IP, IFm, r, h
178
(43)

MMP2 Antibody (8B4)

sc-13595mouse IgG1 κ(h)WB, IP, IF, IHC(P), ELISAm, r, h
236
(23)

MMP2 Antibody (4D3)

sc-53630mouse IgG1 κ557-569 (h)WB, IP, IF, IHC(P)m, r, h
87
(8)

MMP-3 Antibody (1B4)

sc-21732mouse IgG1317-327 (h)WB, IP, IF, IHC(P)m, r, h
73
(20)

MMP-3 Antibody (F-1)

sc-271230mouse IgG1 κ443-476 (h)WB, IP, IF, ELISAm, r, h
3
(2)

MMP-3/10 Antibody (F-10)

sc-374029mouse IgG1 κ178-477 (h)WB, IP, IF, ELISAm, r, h
9
(5)

MMP-7 Antibody (A-5)

sc-515703mouse IgG1 κFL (h)WB, IP, IF, ELISAh
14
(7)

MMP-7 Antibody (JL07)

sc-80205mouse IgG2b(h)WB, IP, IF, IHC(P)h
31
(8)

MMP-7 Antibody (MM0022-4C21)

sc-101566mouse IgG2(h)WB, IP, IF, IHC(P)h
3
(2)

MMP-8 Antibody (B-1)

sc-514803mouse IgM κ122-166 (h)WB, IP, IF, ELISAm, r, h
6
(5)

Ac-MMP9 Antibody (4A3)

sc-21736mouse IgG1 κ107-115 (h)WB, IF, IHC(P)h
10
(1)

MMP9 Antibody (E-11)

sc-393859mouse IgG2b678-707 (h)WB, IP, IF, IHC(P), ELISAm, r, h
165
(38)

MMP9 Antibody (2C3)

sc-21733mouse IgG1 κ603-614 (h)WB, IP, IF, IHC(P)h
322
(21)

MMP9 Antibody (6-6B)

sc-12759mouse IgG1 κ(h)WB, IP, IF, IHC(P), ELISAh
68
(4)

MMP9 Antibody (7-11C)

sc-13520mouse IgG1 κ(h)WB, IP, IF, IHC(P), ELISAm, r, h
101
(11)

MMP-10 Antibody (LA-12)

sc-80197mouse IgG199-486 (h)WB, IP, IF, IHC(P), FCMh
6
(1)

MMP-11 Antibody (5#)

sc-517445mouse IgG2b κ277-488 (h)WB, IP, IF, IHC(P), ELISAh
1
(0)

MMP-12 Antibody (A-2)

sc-133151mouse IgG2b171-470 (h)WB, IP, IF, ELISAh
4
(3)

MMP-12 Antibody (G-2)

sc-390863mouse IgG1 κ438-453 (m)WB, IP, IF, ELISAm, r, h
13
(1)

MMP-12 Antibody (H-9)

sc-390284mouse IgG2a κ429-463 (m)WB, IP, IF, ELISAm, r

new

(1)

MMP-13 Antibody (C-3)

sc-515284mouse IgG1 κ242-471 (h)WB, IP, IF, ELISAh
38
(10)

MMP-13 Antibody (MM0019-12E10)

sc-101564mouse IgG1(h)WB, IF, IHC(P)h
13
(2)

MMP-21 Antibody (C-7)

sc-398935mouse IgG1 κ241-263 (h)WB, IP, IF, ELISAm, r, h
1
(1)

MMP-26 Antibody (TG-9)

sc-100558mouse IgG2a κ152-262 (h)WB, IP, ELISAh

new

(2)

MMP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MMP-1 siRNA (h)

sc-41552hGene SilencingN/A
19
(0)

MMP-1 shRNA Plasmid (h)

sc-41552-SHhGene SilencingPuromycin
19
(0)

MMP-1 shRNA (h) Lentiviral Particles

sc-41552-VhGene SilencingPuromycin
19
(0)

MMP-1a siRNA (m)

sc-149479mGene SilencingN/A0
(0)

MMP-1a shRNA Plasmid (m)

sc-149479-SHmGene SilencingPuromycin0
(0)

MMP-1a shRNA (m) Lentiviral Particles

sc-149479-VmGene SilencingPuromycin0
(0)

MMP-1b siRNA (m)

sc-149480mGene SilencingN/A0
(0)

MMP-1b shRNA Plasmid (m)

sc-149480-SHmGene SilencingPuromycin0
(0)

MMP-1b shRNA (m) Lentiviral Particles

sc-149480-VmGene SilencingPuromycin0
(0)

MMP2 siRNA (h)

sc-29398hGene SilencingN/A
26
(0)

MMP2 shRNA Plasmid (h)

sc-29398-SHhGene SilencingPuromycin
26
(0)

MMP2 shRNA (h) Lentiviral Particles

sc-29398-VhGene SilencingPuromycin
26
(0)

MMP2 siRNA (m)

sc-37264mGene SilencingN/A0
(0)

MMP2 shRNA Plasmid (m)

sc-37264-SHmGene SilencingPuromycin0
(0)

MMP2 shRNA (m) Lentiviral Particles

sc-37264-VmGene SilencingPuromycin0
(0)

MMP2 siRNA (r)

sc-108049rGene SilencingN/A
5
(0)

MMP2 shRNA Plasmid (r)

sc-108049-SHrGene SilencingPuromycin
5
(0)

MMP2 shRNA (r) Lentiviral Particles

sc-108049-VrGene SilencingPuromycin
5
(0)

MMP2 siRNA (bovine)

sc-155986bovineGene SilencingN/A0
(0)

MMP2 shRNA Plasmid (bovine)

sc-155986-SHbovineGene SilencingPuromycin0
(0)

MMP2 shRNA (bovine) Lentiviral Particles

sc-155986-VbovineGene SilencingPuromycin0
(0)

MMP-3 siRNA (h)

sc-29399hGene SilencingN/A
9
(0)

MMP-3 shRNA Plasmid (h)

sc-29399-SHhGene SilencingPuromycin
9
(0)

MMP-3 shRNA (h) Lentiviral Particles

sc-29399-VhGene SilencingPuromycin
9
(0)

MMP-3 siRNA (m)

sc-37265mGene SilencingN/A
6
(0)

MMP-3 shRNA Plasmid (m)

sc-37265-SHmGene SilencingPuromycin
6
(0)

MMP-3 shRNA (m) Lentiviral Particles

sc-37265-VmGene SilencingPuromycin
6
(0)

MMP-3 siRNA (r)

sc-61874rGene SilencingN/A
6
(0)

MMP-3 shRNA Plasmid (r)

sc-61874-SHrGene SilencingPuromycin
6
(0)

MMP-3 shRNA (r) Lentiviral Particles

sc-61874-VrGene SilencingPuromycin
6
(0)

MMP-7 siRNA (h)

sc-41553hGene SilencingN/A
7
(0)

MMP-7 shRNA Plasmid (h)

sc-41553-SHhGene SilencingPuromycin
7
(0)

MMP-7 shRNA (h) Lentiviral Particles

sc-41553-VhGene SilencingPuromycin
7
(0)

MMP-7 siRNA (m)

sc-41554mGene SilencingN/A0
(0)

MMP-7 shRNA Plasmid (m)

sc-41554-SHmGene SilencingPuromycin0
(0)

MMP-7 shRNA (m) Lentiviral Particles

sc-41554-VmGene SilencingPuromycin0
(0)

MMP-7 siRNA (r)

sc-108053rGene SilencingN/A
2
(0)

MMP-7 shRNA Plasmid (r)

sc-108053-SHrGene SilencingPuromycin
2
(0)

MMP-7 shRNA (r) Lentiviral Particles

sc-108053-VrGene SilencingPuromycin
2
(0)

MMP-8 siRNA (h)

sc-35949hGene SilencingN/A
1
(0)

MMP-8 shRNA Plasmid (h)

sc-35949-SHhGene SilencingPuromycin
1
(0)

MMP-8 shRNA (h) Lentiviral Particles

sc-35949-VhGene SilencingPuromycin
1
(0)

MMP-8 siRNA (m)

sc-35950mGene SilencingN/A
2
(1)

MMP-8 shRNA Plasmid (m)

sc-35950-SHmGene SilencingPuromycin
2
(1)

MMP-8 shRNA (m) Lentiviral Particles

sc-35950-VmGene SilencingPuromycin
2
(1)

MMP9 siRNA (h)

sc-29400hGene SilencingN/A
56
(0)

MMP9 shRNA Plasmid (h)

sc-29400-SHhGene SilencingPuromycin
56
(0)

MMP9 shRNA (h) Lentiviral Particles

sc-29400-VhGene SilencingPuromycin
56
(0)

MMP9 siRNA (m)

sc-29401mGene SilencingN/A
7
(0)

MMP9 shRNA Plasmid (m)

sc-29401-SHmGene SilencingPuromycin
7
(0)

MMP9 shRNA (m) Lentiviral Particles

sc-29401-VmGene SilencingPuromycin
7
(0)

MMP9 siRNA (bovine)

sc-155990bovineGene SilencingN/A0
(0)

MMP9 shRNA Plasmid (bovine)

sc-155990-SHbovineGene SilencingPuromycin0
(0)

MMP9 shRNA (bovine) Lentiviral Particles

sc-155990-VbovineGene SilencingPuromycin0
(0)

MMP9 siRNA (canine)

sc-270247canineGene SilencingN/A0
(0)

MMP9 shRNA Plasmid (canine)

sc-270247-SHcanineGene SilencingPuromycin0
(0)

MMP9 shRNA (canine) Lentiviral Particles

sc-270247-VcanineGene SilencingPuromycin0
(0)

MMP-10 siRNA (h)

sc-41555hGene SilencingN/A
1
(0)

MMP-10 shRNA Plasmid (h)

sc-41555-SHhGene SilencingPuromycin
1
(0)

MMP-10 shRNA (h) Lentiviral Particles

sc-41555-VhGene SilencingPuromycin
1
(0)

MMP-10 siRNA (m)

sc-41556mGene SilencingN/A
1
(0)

MMP-10 shRNA Plasmid (m)

sc-41556-SHmGene SilencingPuromycin
1
(0)

MMP-10 shRNA (m) Lentiviral Particles

sc-41556-VmGene SilencingPuromycin
1
(0)

MMP-11 siRNA (h)

sc-35947hGene SilencingN/A
1
(0)

MMP-11 shRNA Plasmid (h)

sc-35947-SHhGene SilencingPuromycin
1
(0)

MMP-11 shRNA (h) Lentiviral Particles

sc-35947-VhGene SilencingPuromycin
1
(0)

MMP-11 siRNA (m)

sc-35948mGene SilencingN/A
1
(0)

MMP-11 shRNA Plasmid (m)

sc-35948-SHmGene SilencingPuromycin
1
(0)

MMP-11 shRNA (m) Lentiviral Particles

sc-35948-VmGene SilencingPuromycin
1
(0)

MMP-12 siRNA (h)

sc-41557hGene SilencingN/A
2
(0)

MMP-12 shRNA Plasmid (h)

sc-41557-SHhGene SilencingPuromycin
2
(0)

MMP-12 shRNA (h) Lentiviral Particles

sc-41557-VhGene SilencingPuromycin
2
(0)

MMP-12 siRNA (m)

sc-41558mGene SilencingN/A0
(0)

MMP-12 shRNA Plasmid (m)

sc-41558-SHmGene SilencingPuromycin0
(0)

MMP-12 shRNA (m) Lentiviral Particles

sc-41558-VmGene SilencingPuromycin0
(0)

MMP-13 siRNA (h)

sc-41559hGene SilencingN/A
12
(0)

MMP-13 shRNA Plasmid (h)

sc-41559-SHhGene SilencingPuromycin
12
(0)

MMP-13 shRNA (h) Lentiviral Particles

sc-41559-VhGene SilencingPuromycin
12
(0)

MMP-13 siRNA (m)

sc-41560mGene SilencingN/A
4
(0)

MMP-13 shRNA Plasmid (m)

sc-41560-SHmGene SilencingPuromycin
4
(0)

MMP-13 shRNA (m) Lentiviral Particles

sc-41560-VmGene SilencingPuromycin
4
(0)

MMP-19 siRNA (h)

sc-106229hGene SilencingN/A
1
(0)

MMP-19 shRNA Plasmid (h)

sc-106229-SHhGene SilencingPuromycin
1
(0)

MMP-19 shRNA (h) Lentiviral Particles

sc-106229-VhGene SilencingPuromycin
1
(0)

MMP-19 siRNA (m)

sc-149478mGene SilencingN/A0
(0)

MMP-19 shRNA Plasmid (m)

sc-149478-SHmGene SilencingPuromycin0
(0)

MMP-19 shRNA (m) Lentiviral Particles

sc-149478-VmGene SilencingPuromycin0
(0)

MMP-20 siRNA (h)

sc-41561hGene SilencingN/A
1
(0)

MMP-20 shRNA Plasmid (h)

sc-41561-SHhGene SilencingPuromycin
1
(0)

MMP-20 shRNA (h) Lentiviral Particles

sc-41561-VhGene SilencingPuromycin
1
(0)

MMP-20 siRNA (m)

sc-41562mGene SilencingN/A0
(0)

MMP-20 shRNA Plasmid (m)

sc-41562-SHmGene SilencingPuromycin0
(0)

MMP-20 shRNA (m) Lentiviral Particles

sc-41562-VmGene SilencingPuromycin0
(0)

MMP-21 siRNA (h)

sc-62627hGene SilencingN/A0
(0)

MMP-21 shRNA Plasmid (h)

sc-62627-SHhGene SilencingPuromycin0
(0)

MMP-21 shRNA (h) Lentiviral Particles

sc-62627-VhGene SilencingPuromycin0
(0)

MMP-21 siRNA (m)

sc-62628mGene SilencingN/A0
(0)

MMP-21 shRNA Plasmid (m)

sc-62628-SHmGene SilencingPuromycin0
(0)

MMP-21 shRNA (m) Lentiviral Particles

sc-62628-VmGene SilencingPuromycin0
(0)

MMP-23 siRNA (h)

sc-41563hGene SilencingN/A0
(0)

MMP-23 shRNA Plasmid (h)

sc-41563-SHhGene SilencingPuromycin0
(0)

MMP-23 shRNA (h) Lentiviral Particles

sc-41563-VhGene SilencingPuromycin0
(0)

MMP-23 siRNA (m)

sc-41564mGene SilencingN/A0
(0)

MMP-23 shRNA Plasmid (m)

sc-41564-SHmGene SilencingPuromycin0
(0)

MMP-23 shRNA (m) Lentiviral Particles

sc-41564-VmGene SilencingPuromycin0
(0)

MMP-26 siRNA (h)

sc-106230hGene SilencingN/A0
(0)

MMP-26 shRNA Plasmid (h)

sc-106230-SHhGene SilencingPuromycin0
(0)

MMP-26 shRNA (h) Lentiviral Particles

sc-106230-VhGene SilencingPuromycin0
(0)

MMP-27 siRNA (h)

sc-96557hGene SilencingN/A0
(0)

MMP-27 shRNA Plasmid (h)

sc-96557-SHhGene SilencingPuromycin0
(0)

MMP-27 shRNA (h) Lentiviral Particles

sc-96557-VhGene SilencingPuromycin0
(0)

MMP Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

MMP2 (h): 293 Lysate

sc-176407h
2
(1)

MMP9 (h2): 293T Lysate

sc-176046h2
2
(0)

MMP CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MMP-1 CRISPR/Cas9 KO Plasmid (h)

sc-416533Gene Knockouth0
(0)

MMP-1 HDR Plasmid (h)

sc-416533-HDRHomology Directed Repairh0
(0)

MMP2 CRISPR/Cas9 KO Plasmid (h)

sc-400126Gene Knockouth0
(0)

MMP2 HDR Plasmid (h)

sc-400126-HDRHomology Directed Repairh0
(0)

MMP-3 CRISPR/Cas9 KO Plasmid (h)

sc-400727Gene Knockouth0
(0)

MMP-3 HDR Plasmid (h)

sc-400727-HDRHomology Directed Repairh0
(0)

MMP9 CRISPR/Cas9 KO Plasmid (h)

sc-400083Gene Knockouth0
(0)

MMP9 HDR Plasmid (h)

sc-400083-HDRHomology Directed Repairh0
(0)

MMP9 CRISPR/Cas9 KO Plasmid (m)

sc-421679Gene Knockoutm0
(0)

MMP9 HDR Plasmid (m)

sc-421679-HDRHomology Directed Repairm0
(0)

MMP9 CRISPR/Cas9 KO Plasmid (r)

sc-437355Gene Knockoutr0
(0)

MMP9 HDR Plasmid (r)

sc-437355-HDRHomology Directed Repairr0
(0)

MMP-12 CRISPR/Cas9 KO Plasmid (h)

sc-401853Gene Knockouth0
(0)

MMP-12 HDR Plasmid (h)

sc-401853-HDRHomology Directed Repairh0
(0)

MMP-12 CRISPR/Cas9 KO Plasmid (m)

sc-421667Gene Knockoutm0
(0)

MMP-12 HDR Plasmid (m)

sc-421667-HDRHomology Directed Repairm0
(0)

MMP-13 CRISPR/Cas9 KO Plasmid (h)

sc-400626Gene Knockouth0
(0)

MMP-13 HDR Plasmid (h)

sc-400626-HDRHomology Directed Repairh0
(0)

MMP-13 CRISPR/Cas9 KO Plasmid (m2)

sc-421670-KO-2Gene Knockoutm0
(0)

MMP-13 HDR Plasmid (m2)

sc-421670-HDR-2Homology Directed Repairm0
(0)

MMP-20 CRISPR/Cas9 KO Plasmid (h)

sc-405838Gene Knockouth0
(0)

MMP-20 CRISPR/Cas9 KO Plasmid (m)

sc-424397Gene Knockoutm0
(0)

MMP-20 HDR Plasmid (m)

sc-424397-HDRHomology Directed Repairm0
(0)

MMP-21 CRISPR/Cas9 KO Plasmid (h)

sc-414131Gene Knockouth0
(0)

MMP CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MMP2 Double Nickase Plasmid (h)

sc-400126-NICGene Knockouth0
(0)

MMP2 Double Nickase Plasmid (h2)

sc-400126-NIC-2Gene Knockouth0
(0)

MMP2 Double Nickase Plasmid (m)

sc-421674-NICGene Knockoutm0
(0)

MMP2 Double Nickase Plasmid (m2)

sc-421674-NIC-2Gene Knockoutm0
(0)

MMP-7 Double Nickase Plasmid (m)

sc-421677-NICGene Knockoutm0
(0)

MMP-7 Double Nickase Plasmid (m2)

sc-421677-NIC-2Gene Knockoutm0
(0)

MMP9 Double Nickase Plasmid (h)

sc-400083-NICGene Knockouth0
(0)

MMP9 Double Nickase Plasmid (h2)

sc-400083-NIC-2Gene Knockouth0
(0)

MMP9 Double Nickase Plasmid (m)

sc-421679-NICGene Knockoutm0
(0)

MMP-13 Double Nickase Plasmid (h)

sc-400626-NICGene Knockouth0
(0)

MMP-13 Double Nickase Plasmid (h2)

sc-400626-NIC-2Gene Knockouth0
(0)

MMP-13 Double Nickase Plasmid (m)

sc-421670-NICGene Knockoutm0
(0)

MMP-13 Double Nickase Plasmid (m2)

sc-421670-NIC-2Gene Knockoutm0
(0)

MMP CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MMP2 CRISPR Activation Plasmid (h)

sc-400126-ACTGene Activationh0
(0)

MMP2 CRISPR Activation Plasmid (h2)

sc-400126-ACT-2Gene Activationh0
(0)

MMP2 CRISPR Activation Plasmid (m)

sc-421674-ACTGene Activationm0
(0)

MMP2 CRISPR Activation Plasmid (m2)

sc-421674-ACT-2Gene Activationm0
(0)

MMP-3 CRISPR Activation Plasmid (h)

sc-400727-ACTGene Activationh0
(0)

MMP-8 CRISPR Activation Plasmid (h)

sc-402089-ACTGene Activationh0
(0)

MMP-8 CRISPR Activation Plasmid (h2)

sc-402089-ACT-2Gene Activationh0
(0)

MMP9 CRISPR Activation Plasmid (h)

sc-400083-ACTGene Activationh0
(0)

MMP9 CRISPR Activation Plasmid (h2)

sc-400083-ACT-2Gene Activationh0
(0)

MMP9 CRISPR Activation Plasmid (m)

sc-421679-ACTGene Activationm0
(0)

MMP-10 CRISPR Activation Plasmid (h)

sc-403174-ACTGene Activationh0
(0)

MMP-11 CRISPR Activation Plasmid (h)

sc-404334-ACTGene Activationh0
(0)

MMP-12 CRISPR Activation Plasmid (h)

sc-401853-ACTGene Activationh0
(0)

MMP-12 CRISPR Activation Plasmid (h2)

sc-401853-ACT-2Gene Activationh0
(0)

MMP-13 CRISPR Activation Plasmid (h)

sc-400626-ACTGene Activationh0
(0)

MMP-13 CRISPR Activation Plasmid (m)

sc-421670-ACTGene Activationm0
(0)

MMP-19 CRISPR Activation Plasmid (h)

sc-404370-ACTGene Activationh0
(0)