epitope mapping within an internal region of GLP-1 of human origin
recommended for detection of precursor and processed active GLP-1 of mouse, rat and human origin by IF and ELISA; non cross-reactive with Glucagon or GLP-2; also reactive with additional species, including equine, canine, bovine and porcine
GLP-1 Background Information Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels (1). Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the Glucagon family of hormones (2). GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth (3,4). VIP causes vasodilation resulting in the lowering of blood pressure (5). PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone (6).
GLP-1 (F-15) Product Citations
See how others have used GLP-1 (F-15): sc-26637 antibody and or GLP-1 (F-15) antibody conjugates.
