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home » Transcription Regulators » Smad Antibody / Smad Antibodies » Smad5 (T-13): sc-26419

Smad5 (T-13) Antibody: sc-26419

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within an internal region of Smad5 of human origin
  • recommended for detection of Smad5 of mouse, rat and human origin by WB, IF and ELISA
  • blocking peptide, sc-26419 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-26419 X, 200 µg/0.1 ml
 
Additional Smad Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SMAD5 4090 5q31.2 NM_001001419, NM_001001420, NM_005903 Q99717
 603110
Mouse Smad5 17129 13 B1 P97454
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Smad5 (T-13) sc-26419 200 µg/ml $279
Smad5 (T-13) P sc-26419 P
(peptide)
 100 µg/0.5 ml $61
Smad5 (T-13) X sc-26419 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Smad5 siRNA (h) sc-38378 10 µM $258
Smad5 siRNA (m) sc-38379 10 µM $258
Smad5 siRNA (r) sc-63290 10 µM $258
Smad5 (h)-PR sc-38378-PR 10 µM $23
Smad5 (m)-PR sc-38379-PR 10 µM $23
Smad5 (r)-PR sc-63290-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Smad5 shRNA Plasmid (h) sc-38378-SH 20 µg $520
Smad5 shRNA Plasmid (m) sc-38379-SH 20 µg $520
Smad5 shRNA Plasmid (r) sc-63290-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Smad5 shRNA (h) Lentiviral Particles sc-38378-V 200 µl $625
Smad5 shRNA (m) Lentiviral Particles sc-38379-V 200 µl $625
Smad5 shRNA (r) Lentiviral Particles sc-63290-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
DU 145 Cell Lysate sc-2268 500 µg/200 µl $104
PC-3 Cell Lysate sc-2220 500 µg/200 µl $104
HeLa nuclear extract sc-2120 1000 µg $143
Sol8 Cell Lysate sc-2249 500 µg/200 µl $104

Smad5 Background Information
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGF∫/BMP signaling (1). Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF∫ and activin-mediated growth modulation (2-5,8). Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members (6). Smad6 and Smad7 regulate the response to activin/TGF∫ signaling by interfering with TGF∫-mediated phosphorylation of other Smad family members (7,8).